Dosing Flashcards
Dose of diclofenac
- 50 mg q8-12 hours
- Max 150 mg daily
Dose of ibuprofen
- 400 mg q4-6 hours
- Max 3200 mg (acute) or 2400 mg (chronic) per day
OTC:
200 mg TDS
Dose of naproxen sodium
- 275 -550 mg q12 hours
- Max 1375 mg (acute) or 1100 mg (chronic)
OTC:
- 220 mg q8-12 hours
Dose of celecoxib
- 200 mg daily or 100 mg q12 hours
- Max 400 mg per day
Dose of etoricoxib
- 30-60 mg once daily
- Max 120 mg (acute up to 8 days) or 60 mg (chronic) per day
Dose of methotrexate
- Initial: 7.5 mg once weekly
- Increase 2.5-5 mg / week q4-12 weeks
- Target: 15 mg / week within 4-6 weeks of initiation
- Max 25 mg / week
Dose of sulfasalazine
- Initial 500 mg OD or BD
- Increase by 500 mg / week
- Target: 1 g BD
- Max 3 g/day
Dose of hydroxychloroquine
- 200-400 mg in 1-2 divided doses
- Max 5 mg/kg/day
Dose of leflunomide
- 100 mg/day x 3 days
- Followed by 20 mg daily
Dose of glucocorticoids for RA bridge
Not more than 7.5 mg of prednisolone per day for 3 months
Dose of colchicine
Either:
- One-off treatment with 1 mg loading dose
- Followed by a single dose of 0.5 mg one hour later
or
- 0.5 mg BD or TDS until flare resolution
Max 1.5 mg daily
Dose of allopurinol
- Initiate not more than 100 mg per day (or 50 mg in CKD)
- Titrate with 50-100 mg increments q2-8 weeks
- Usual maintenance dose > 300 mg per day
- Max 800-900 mg per day
Dose of febuxostat
- Initiate not more than 40 mg per day
- Increase to 80 mg per day if target not met after 2-4 weeks
Dose of probenecid
- Initiate 250 mg BD x 1 week, f/b 500 mg BD
- Titrate with 500 mg increments q4 weeks if not controlled
- Usual maintenance dose at most 2 g per day
Dose of romosozumab
SC once monthly, up to 12 months
Dose of zolendronic acid
IV 5 mg every year as a 30 min infusion. Ensure adequate hydration prior to infusion.
Dose of risedronate
PO 35 mg every week
Dose of ibandronate
PO 150 mg monthly
Dose of alendronate
PO 70 mg every week
Dose of denosumab
SC once every 6 months
Dose of calcium supplementation
1000 mg elemental Ca per day (>50 y.o.)
800 mg elemental Ca per day (50 y.o. and below)
Supplement if daily intake 700 mg elemental Ca/day
Dose of vit D supplementation
800 IU per day
Dose of meloxicam
7.5-15 mg OD
Max 15 mg
Dose of voltaren gel
1% diclofenac
3-4 times/day
Max 2-3 weeks
Dose of kefentech plaster
30 mg ketoprofen
BD
Max 10 days
Dose of fastum gel
2.5% ketoprofen
2-3 times/day
Max 10 days
Dose of paracetamol
1000 mg q6 hours, up to TDS
Max 3000 mg
4000 mg if clinically supervised
Dose of anarex
450 mg paracetamol + 35 mg orphenadrine
2 tablets q6 hours, up to TDS
Max 6 tablets
Dose of tramadol
25-50 mg TDS
Max 400 mg
Dose of glucocorticoid for acute gout
30-40 mg OD, up to 0.5 mg/kg/day
Until gout resolution, taper off over 7 days
