Dosages NMBs, LAs Flashcards
What is the dose of Succinylcholine?
Onset:
Duration:
Dose: 1 mg/kg IV
Onset: 30-60 seconds
Duration: 3-5 minutes
What is the dose of dantrolene?
2mg/kg IV
Repeat doses until symptoms subside or 10mg/kg IV
Myasthenia Gravis patients are _________ to Succinylcholine. Why?
What is the dose of SCh for MG patients?
Resistant to SCh. More SCh is needed because the ACh receptors that are left do not function as well.
1.5-2.0 mg/kg
For a patient with burns needing intubation, how can we offset the resistance to non-depolarizing blockers the burn causes?
1.2 mg/kg dose of Rocuronium
What is the intubating dose, onset and duration of Pancuronium?
- Dose: 0.1mg/kg;
- Onset: 3-5 minutes;
- Duration: 60-90 minutes
What is the intubating dose, onset, and duration of Vecuronium?
- Intubating Dose: 0.1 mg/kg
- Onset: 3-5 minutes
- Duration: 20-35 minutes
What is the normal intubating dose, onset and duration of Rocuronium?
- Dose: 0.6 mg/kg
- Onset: 3-5 minutes
- Duration: 20-35 minutes
What is the RSI intubating dose, onset and duration of Rocuronium?
- Dose: 1.2 mg/kg
- Onset: 1-2 minutes
- Duration: 60-90 minutes
What is the intubating dose, onset and duration of Cisatracurium?
- Intubating Dose: 0.1 mg/kg;
- Onset: 3-5 minutes;
- Duration of action: 20-35 minutes
What is the intubating dose, onset and duration of Mivacurium?
- Intubating Dose: 0.15 mg/kg;
- Onset: 2-3 minutes (Conditions less desirable);
- Duration: 12-20 minutes
What is the dosage of neostigmine and its max?
40 - 70 mcg/kg
max: 5mg
What is the dosage of edrophonium?
0.5 - 1 mg/kg
What is the dose of Atropine?
7 - 10 mcg/kg
What is the Sugammadex dose for a moderate block?
2 mg/kg
What is the Sugammadex dose for a deep block?
4 mg/kg
What is the sugammadex dose for an extreme block?
8 - 16 mg/kg
What drug and dose would be a good choice for a recurarizing patient in the PACU?
Why might this be a good choice?
- Neostigmine 0.05 mg/kg IV (40-70mcg/kg)
- Longer duration of action (60min)
What is the dose and max for glycopyrrolate?
7 - 15 mcg/kg
1mg maximum
MAGA: What is the intra-op infusion dose of lidocaine?
1 mg/kg over an hour
What is the IV dose of Lidocaine? (bolus and drip)
- 1 to 2 mg/kg IV (initial bolus) over 2 - 4 min.
- 1 to 2 mg/kg/hour (drip)
What is Lidocaine’s max infiltration dose? (with and without Epi)
- 300 mg plain
- 500 mg with Epi
What is the max dose of prilocaine?
600 mgs
What is the treatment and dose for methemoglobinemia secondary to prilocaine overdose?
Methylene Blue
- 1 to 2 mg/kg IV over 5 mins (initial dose)
- Total dose not to exceed 8 mg/kg
Benzocaine
Onset:
Duration:
Dose:
onset: rapid
duration: 30-60 min
Dose: 200-300 mg = 20% spray
Lidocaine max single dose
Infiltration:
Topical:
Epidural:
Spinal:
PNB:
- Infiltration: 300mg or 500mg with Epi
- Topical: 300 mg
- Epidural: 300mg or 500mg with Epi
- Spinal: 100mg
- PNB: 300mg or 500mg with Epi
Prilocaine Recommended Max Single Dose for infiltration/IVRA/PNB/Epidural?
600 mg
Bupivacaine Recommended Max Single Dose
Bupivacaine Recommended Max Single Dose with/Epi
Bupivacaine Recommended Max Single Dose for Spinal
175 mg
225 mg w/ Epi
Spinal max: 20 mg
Eutectic Mixture of LA (EMLA) contains what two local anesthetics?
Dose:
Onset:
Lidocaine 2.5% + Prilocaine 2.5% = 5% LA
Dose: 1 to 2 g/ 10 cm² area
Onset: 45 mins
What is the dose of bupivacaine for the scenario below?
5 ft tall patient = _____mL of ____% Bupivacaine
+ ______ mL for every inch above…. 2 cc total ( 1½ hours to 2 hours)
1 mL of 0.75% Bupivacaine
0.1 mL
For someone who is 5’5”, you will give 1.5 mL of 0.75% bupivacaine for a SAB.
What makes up the tumescent solution?
- Diluted Lidocaine (0.05% to 0.1%)
- Epinephrine 1:100,000
What is the dose for Regional Anesthesia Lidocaine with Epi?
7 mg/kg
Highly diluted Lidocaine with Epi Tumescent dose.
35 to 55 mg/kg
What is the bolus dose of Lipid Emulsion?
1.5 mL/kg of 20% lipid emulsion
What is the infusion dose of lipid emulsion?
How long should it be given?
0.25 mL/kg/minute for at least 10 minutes
What is the max total dose for lipid emulsion that should be given?
8 mL/kg
If cardiac arrest occurs with LAST syndrome, how should our epinephrine dosing change?
Small doses (10mcg - 100mcg boluses) are preferred with LAST ACLS.
What is the treatment for methemoglobinemia? What is the max dosage?
Methylene blue 1mg/kg over 5min
max: 8 mg/kg
What is the dose for Atenolol?
5mg q10min IV
What is the dose of metoprolol?
1mg q5min (Given in 5mg “blocks”)
What is the initial dose for esmolol?
20-30mg IV
What is the normal dosing of phenylephrine?
50-100mcg IV push
What is the dose for labetalol? How long would it take to see max effect from IV dose?
2.5 - 5mg IV; 10mg max
IV max effect 5-10 min
What is the IV push dose of epinephrine?
How long does it last?
- 2-8mcg IVpush
- 1-5 min
What is the infusion dose of epinephrine for β2 effects?
1-2 mcg/min
What is the infusion dose of epinephrine for β1 effects?
4 mcg/min
What is the infusion dose of epinephrine for predominantly α effects?
10-20 mcg/min
Which SNS agonist can be given IM? What dose?
Why would this be done?
- Ephedrine IM 50mg
- Long lasting increase in BP for OB patients.
What is the dose of Nitroprusside?
Initial: 0.3 mcg/kg/min
Tritrate slowly to 2 mcg/kg/min
What is the nitroglycerin dose?
Initial: 5 - 10 mcg/min
What is the initial dose of hydralazine?
2.5mg IV
What is the dose of nicardipine?
5mg/hr (↑2.5mg x4hr)
max 15mg/hr
What is the single IV push dose for ephedrine?
5-10mg IV
What is the single IV dose for vasopressin?
1-2 units IV
