Dosages Induction Meds Flashcards
What is the dose for Thiopental?
How much is in the brain 30 minutes post-administration? Why?
- 4mg/kg IV
- 10% in the braine after admin. Rapid redistribution to skeletal muscles occurs.
What is the IV methohexital dose?
What if it needs to be given rectally?
- 1.5 mg/kg IV
- 20 - 30 mg/kg PR
For Propofol, what are the doses for:
1. Induction
2. Maintenance
3. Conscious sedation
- Induction = 1.5 - 2.5 mg/kg IV
- Maintenance = 100 - 300 μg/kg/min
- Conscious sedation = 25 - 100 μg/kg/min
For Propofol, what are the doses for:
1. Induction
2. Maintenance
3. Conscious sedation
- Induction = 1.5 - 2.5 mg/kg IV
- Maintenance = 100 - 300 μg/kg/min
- Conscious sedation = 25 - 100 μg/kg/min
What is the induction dose of propofol in adults? Children?
- Adults: 1.5-2.5 mg/kg IV
- Pediatrics: higher doses due to larger central volume and clearance rate.
What is the conscious sedation dose of propofol?
- 25 - 100 μg/kg/min
What is the sub-hypnotic dosing for propofol?
- 10 - 15 mg IV, followed by 10 mcg/kg/min
What is the anti-pruritic dosing of propofol?
- 10 mg IV
What is the anti-convulsant dosing of propofol?
1mg/kg IV
What is the induction dose for etomidate?
- 0.3 mg/kg IV
What can be administered with etomidate to prevent involuntary myoclonic movements?
Fentanyl 1-2 μg/kg IV
What is the induction dose of ketamine IV?
What if it is given IM?
- 0.5 - 1.5 mg/kg IV
- 4 - 8 mg/kg IM
What is the maintenance dosing of ketamine?
- 0.2 - 0.5 mg/kg IV
- 4 - 8 mg/kg IM
What is the subanesthetic/analgesic dose of ketamine?
- 0.2 - 0.5 mg/kg IV
What is the post-operative sedation and analgesia dosing for ketamine in pediatric cardiac surgery cases?
1-2 mg/kg/hour
What is the neuraxial epidural analgesia dosing of ketamine?
What about intrathecal route?
- 30mg epidural
- 5 - 50 mg via intrathecal/spinal/subarachnoid
What drug and dosing should be used to treat excessive salivary secretions from ketamine administration?
Glycopyrrolate: 0.2mg
At what dosing will the ICP increasing effects of ketamine plateau?
- 2mg/kg IV