dopamine precursors

Question 1

are they associated with impulse control disorders

Answer 1

yes

Question 1

which drug should you avoid with levodopa

Answer 1

amisulpride - predicted to decrease effects of levodopa
(both can also cause sedation)

Question 2

severe interaction between levodopa and antipsychotics

Answer 2

they decrease the effects of levodopa. for most, avoid or monitor worsening pakinsonian symptoms. they also both cause sedation and increase risk of hypotension. some might decrease absorption of levodopa

Question 3

interactions between levodopa and MAOIs

Answer 3

phenelzine, tranylcypromine, isocarboxazid
levodopa increases risk of hypertensive crisis when given with these.
avoid and for 14 days after stopping MAOI

Question 4

Co-beneldopa is a mixture of benserazide hydrochloride and levodopa in mass proportions corresponding to how many parts of each compound?

Answer 4

1 part of benserazide and 4 parts of levodopa.

Question 5

When transferring patients from another levodopa/dopa-decarboxylase inhibitor preparation, the previous preparation should be discontinued..

Answer 5

12 h before, although interval can be shorter

Question 6

When switching from modified-release levodopa to dispersible co-beneldopa, reduce dose by approximately …

Answer 6

30%

Question 7

this medicine may colour your urine. this is harmless. what colour?

Answer 7

red