Dopamine Flashcards
(22 cards)
What happens every time you impulse search or click on link on the internet?
It messes with your dopamine, with your mesolimbic system in a very similar manner to PMO or gaming. ANd this will remarkedly cut into your motivation, energy, and focus capacity.
1st strategy to do everytime you feel like surfing the internet or clicking on a link to take a break?
1) remind yourself of card 1. 2) meditate or 1min exercise (e.g. calf raises)
Alex Becker on how your brain works?
It’s always looking for the shortest path to achieve certain goals
Alex Becker on how dopamine works
It’s used to reward/motivate yourself to achieve goals
Alex Becker on why your motivation is low
Your motivation’s low because video games, phones, consuming info from internet, porn have all hijacked your brain, making your brain think those are real goals and behaviors. Since it’s a shorter path to achieve those goals than real behavior, your brain will release dopamine to motivate you to do those virtual things and not real things
What are two interesting things about the rats pressing the dopamine levers?
it replaced their motivation for beneficial, evolutionarily vital tasks like eating. They literally stopped eating. 2) they literally would walk across electric shocks to hit the dopamine levers
Salamone’s dopamine hypothesis
the primary function of dopamine is to regulate energy expenditure - [https://www.yourbrainonporn.com/relevant-research-and-articles-about-the-studies/dopamine-receptors/putting-desire-on-a-budget-dopamine-and-energy-expenditure-reconciling-reward-and-resources-2012/]
Salamone 1991 and 1994 studies
demonstrated that under free-feeding conditions, preference is not altered by changes in dopamine function; that is, dopamine does not increase incentive or alter food preference when no (or low) work requirement is present. In his studies, however, when obtaining a preferred food is associated with a response cost, dopamine increases the effort an animal will exert
https://www.yourbrainonporn.com/relevant-research-and-articles-about-the-studies/dopamine-receptors/putting-desire-on-a-budget-dopamine-and-energy-expenditure-reconciling-reward-and-resources-2012/
Robinson and Berridge 1993 study
famously described a dissociation between “wanting” and “liking” in addiction where addicts develop “wanting” for drugs without “liking”; that is, the incentive driving compulsive drug seeking is independent of its hedonic consequences
https://www.yourbrainonporn.com/relevant-research-and-articles-about-the-studies/dopamine-receptors/putting-desire-on-a-budget-dopamine-and-energy-expenditure-reconciling-reward-and-resources-2012/
According to Salamone, dopamine does not modulate desire, it puts it on an _________
energy budget
https://www.yourbrainonporn.com/relevant-research-and-articles-about-the-studies/dopamine-receptors/putting-desire-on-a-budget-dopamine-and-energy-expenditure-reconciling-reward-and-resources-2012/
[q: so then what does modulate desire???]
quinpirole
a D2 agonist
what are the three ways generalized activity is measured in rodents?
measured using either the open-field, running wheels or homecage activity monitors
https://www.yourbrainonporn.com/relevant-research-and-articles-about-the-studies/dopamine-receptors/putting-desire-on-a-budget-dopamine-and-energy-expenditure-reconciling-reward-and-resources-2012/
deltaFosB is like a
a sustained molecular switch for addiction [https://www.pnas.org/content/98/20/11042.full]
how long does it take for deltaFosB to decline
6-8 weeks. https://www.yourbrainonporn.com/ybop-articles-on-porn-addiction-porn-induced-problems/the-porn-debate/porn-pseudoscience-and-deltafosb-2013/
We are all hardwired to ______
consume resources in excess of daily requirements . I can’t think of a species that doesn’t” - Mark Edwards, animal nutritionist
Mark Edwards
Animal nutritionist
Adolescents vs adults on deltafosb
Adolescent animals show much greater induction of ΔFosB compared with older animals, consistent with their greater vulnerability for addiction.
https://www.yourbrainonporn.com/ybop-articles-on-porn-addiction-porn-induced-problems/the-porn-debate/porn-pseudoscience-and-deltafosb-2013/
high level summary of the deltaFosB overconsumption feedback loop
continued over-consumption leads to accumulation of ΔFosB → activation of genes → changes in synapses → addiction-related brain changes → cravings, compulsions → continued overconsumption
How long does /u/dasaad3 say it takes to get your dopamine receptors reset?
90 days
agonist
a chemical that binds to a receptor and activates the receptor to produce a biological response
are you no longer addicted after deltaFosB declines?
not necessarily. your sensitized neural pathways can still exist.
Alex Becker on timeline of a dopamine detox
first 2 days are hard. day 3 you noticeably have more motivation for the things that matter. day 5 is when you really start to get a lot of motivation.
