Donor Selection and Testing Exam 6

Question 1

RBCs can be turned into…?

Answer 1

Unmodified, frozen, Leukocyte reduced, irradiated, recovered, rejuventated, and washed

Question 2

Granulocytes can be turned into what kind of product?

Answer 2

Granulocytes only no other modifications or types of product

Question 3

Hematopoietic progenitor cells can be turned into what kind of product?

Answer 3

Fresh or cryopreserved

Question 4

Platelets can be turned into what kind of product?

Answer 4

Unmodified, leukocyte reduced, irradiated, PAS, pathogen reduced, and washed.

Question 5

Plasma can be turned into what kind of product?

Answer 5

Frozen, thawed, liquid, cryo-reduced, and solvent/detergent treated

Question 6

Cryoprecipitate can be turned into what kind of product?

Answer 6

Single unit or pooled

Question 7

What is the ratio for preserving whole blood?

Answer 7

For every 100 mL of whole blood there needs to be 14 mL of anticoagulant.

Question 8

What is the hematocrit of packed RBCs with additive solution?

Answer 8

55% to 65%

Question 9

What is the hematocrit of packed RBCs with no additive solution

Answer 9

65% to 80%

Question 10

A unit of packed RBCs will raise the Hgb by how much?

Answer 10

1 gram or 3% Hct

Question 11

What additive solution is used for pediatric transfusion?

Answer 11

Nutricel or AS-3 because there is no mannitol in it. Mannitol can cause problems with babies. I think nerve issues.

Question 12

FFP expiration date and expires if thawed?

Answer 12

Frozen up to 1 year. After thawing it will expire after 24 hours

Question 13

FFP has to be frozen within how many hours?

Answer 13

8 hours

Question 14

What clotting factors are in FFP?

Answer 14

V and VIII

Question 15

PF24 have to be frozen within how many hours?

Answer 15

24 hours

Question 16

What is the difference between PF24 and FFP?

Answer 16

Slightly reduced levels of Factor VII than FFP

Question 17

Once PF24 is thawed, what is the expiration date?

Answer 17

24 hours

Question 18

Once frozen never thawed PF24 is good for how long?

Answer 18

Up to 1 Year

Question 19

PF24RT24 can be kept at room temperature for how long?

Answer 19

Room temperature up to 24 hours then frozen

Question 20

Once PF24RT24 is frozen it can last for how long?

Answer 20

1 year

Question 21

Once PF24RT24 is thawed for the first time, it can be good for how long?

Answer 21

5 days

Question 22

What is the expiration date for plasma kept at 1-6C?

Answer 22

26 day expiration

Question 23

If thawed plasma (TP) has passed 24 hour thaw expiration can it be stored for longer?

Answer 23

Yes for an additional 4 days (5 days total) however the therapeutic levels of labile factors V and VIII are reduced

Question 24

Platelets obtained from whole blood is called what?

Answer 24

RDP or random donor platelet

Question 25

Platelets obtained using apheresis is called what?

Answer 25

Single donor or single donor platelets

Question 26

How many random donor plates equal 1 single donor platelets?

Answer 26

Aprox. 6 random donor platelet equals 1 single donor platelets

Question 27

1 SDP raises platelet count by how much?

Answer 27

30k to 60k

Question 28

What does cryoprecipitated AHF contain?

Answer 28

Concentration of factor VIII (AHF), fibrinogen, factor XIII, vWF (w/ ADAMTS13), cryglobulin, and fibronectin

Question 29

What is the preparation for cryoprecipitation AHF?

Answer 29

thaw at 1-6C, centrifuged cold hard sping, supernatant expressed, and refrozen within 1 hour.

Question 30

1 unit plasma yields how many units of cryo?

Answer 30

1 unit. An adult dose is 10 units.

Question 31

1 unit of cryo has how much fibrinogen and AHF?

Answer 31

150 mg of fibrinogen and 80 units of AHF