donor deferrals Flashcards
list steps checked during ‘selection: donor ID’
- photographic ID for age
- date of last donation
- deferral status
last deferral period for WBC donation
56 days
list deferral period for double RBC donation
112 days
3 times/year
list deferral period for PLT donation
7 days
24 times/year
list deferral period for plasma donation
28 days
13 times/year
list diseases in which tests are available but will not detect window periods
- chagas
- HBV
- HCV
- HTLV 1 and 2
- WNV
- zika
name diseases in which tests are available but not universally used
- HIV group O strain CMV
list diseases that have no licensed tests available and are only ID from DHQ
- babesiosis
- CJD
- Malaria
list items checked in a mini physical prior to donation
- general appearance
- anemia: hgb/hct
- temperature
- blood pressure
- pulse
- weight
name the allogenic H/H requirments
- M: hgb >13 hct
- F: hgb>12.5, hct>38%
name the autologous H/H requirmens
H/H >11 or 33%
name the temperature cut off for doantions
not to exceed 37.5C or 99.5F
- helps determine bacterial infection
name the cut off for miniphysical blood pressure
less than 180/100 (FDA)
list the pulse requirments in the mini physical
50-100 BPM
name the mini physical weight req
> 110 lbs
what is the purpose of the DHQ
prevents donations from individuals who may be in window period of infectivity or other transmissible diseases
list health risks the DHQ attempts to address
- infectious diseases
- bacterial contamination
- cardiac strain
- birth defects
- caugulopathy
list diseases of interest for travel restrictions
- blood parasites: malaria leichmania
- virus: zika and ebola
- prions: variant CJD
when is the ‘questioning only’ approach used, and for what infectious agent
agents with defined risk but no test
- malaria, prions, ebola
when is the ‘donor testing only’ approach used, and for what infectious agent
donor test available but no questions can distinguish individual risk of infection
- WNV, chagas
when is the ‘questioning and testing’ approach used, and for what infectious agents
both ID risk of infection and effective tests
- HIV, HBV, HCV, zika, babesia, syphilus
when is the ‘use test-negative blood for specific recipients’ approach used, and for what infectious agent
high prevalence of infectious agent in donors but ID subset of recipients benefit from tested negative blood
- CMV
when is the ‘test blood component’ approach used and for what infectious agent
infectious agent not detectable in donor sample
- bacteria (platelets)
what are teh requirments for blood collection
- BP cuff inflated
- 16g needle
- cannot exceed 15 minutes
name the most common collection reaction in donors
vasovagal
- brachycardia (slow heart rate)
name the donor reaction most common in 1st time donors
hyperventilation
name the most uncommon donor reaction in blood donations
hypotensive shock
- tachycardia (fast heart rate)
name the 3 types of donors
- allogenic
- directed
- autologous
name the collection types for autologous donation
- pre-op
- acute normovolemic hemodilution
- intraoperative collection
- post operative cell salvage
name the risk factor of autologous donations
TACO - getting too much blood
in what scenario can an underweight donor be accepted
- autologous donation
- math eq: (donor weight/110)=(anticoag/450mL)
as of 2018, what are blood products tested for
- t Cruzi Ab
- HBsAb and HBcAb
- HCAb
- HIV
- HTLV
- syphilis
- WBV
- babesia
list the required tests of donated blood
- ABO
- D phenotype
- Ab screen
- infectious disease testing
- QC
how is QC ran on donated blood
- platelet bacterial testing
- WBC count on leukoreduced units (filtred)
syphilis test method and deferral time
FTA-ABS
12 months post treatment
HBV test method and deferral time
- HBV DNA, HBsAg, anti HBc
- neutralization/NAT
- permenent
HIV (1&2) test method and deferral time
- NAT
- permanent
HCV test method and deferral time
- pool HIV NAT
- permanent?
HTLV test method and deferral time
- anti-HTLV ChLIA
- permanent
T cruzi test method and deferral time
- ChLIA on first time donors
- indefinite
WNV test method and deferral time
- NAT
- 120 days
- tested in pools until first pos in mosqito season
Bebesiosis test method and deferral time
- NAT and DHQ
- 2 years from reactive test
- year round single donor test in endemic regions (east coast)
Zika test method and deferral time
- NAT
- 4 weeks
how long are donor records kept for and why
10 years
- past units given reviewed for potential infections transmission