donepezil Flashcards
1
Q
what class of drug is it?
A
acetylcholinesterase inhibitor
2
Q
used to treat?
A
mild to moderate Alzheimer’s
3
Q
MOA
A
increase acetylcholine to educe dementia syymptoms
4
Q
caution in who
A
asthma
copd
sick sinus syndrome -dysfunction of the sinoatrial node causing abnormal heart rhythm
susceptible to peptic ulcers
supraventricular conduction abnormalities
5
Q
interactions
A
increase bradycardia with beta blockers
anti-muscarinics
6
Q
side effects
A
agitation dizziness headache abnormal dreams fatigue aggression insomnia pruitis
7
Q
thing to consider
A
start at low dose
eliminated in liver so may need to reduce dose in hepatic impairment or use alternative
8
Q
interactions with ggalatamine
A
erythromycin
ketoconazole
paroxetine
9
Q
rivastigamine
A
other potential symptoms
weight loss, increase salivation, tremor
avoid in bladder outlet obstruction, seizures
