Alcohol Dependency Flashcards

1
Q

What does alcohol abuse cost the NHS

A

21 billion

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2
Q

How much does it cost the NHS

A

20 billion

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3
Q

What percentage of 16-25 suffer from dependency

How many people overdrink

A

4 percent

1/4

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4
Q

What are the risk factors for dependency

A
Anxiety 
Depression 
Social isolation/ relationship breakdown 
Genetics 
Life events adverse
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5
Q

What is alcohol converted into

A

Acetylaldehyde and then acetate

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6
Q

What is a common disorder seen with acetylaldehyde metabolism

A

Aldh2
Asian flushing syndrome

Symptoms include 
Flush on face
Blurred vision 
Headache 
Tachycardia and hypotension 
Dyspnoea 
Anxiety 
Vertigo 
Nausea and vomiting
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7
Q

What time are symptoms of alcoholcodependency

A
Tachycardia 
Hypotension
Confusion 
Hepatic fetor 
Tremors 
Signs of liver disease - spider naevi, gynaecomastica , jaundice hepatomegaly ascites
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8
Q

Wernikes korsakoff syndrome

What are the symptoms

A
Ataxia 
Confusion
Opthamlgopegia 
Memory loss
Peripheral neuropathy
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9
Q

Questions to ask

A

Cage. Cut down aggression or annoyed but confrontation of drinking. Guilty. Eye opener/ first thing in the morning.

Over 2 then dependency

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10
Q

What can you ask as part of sadq

A
Desire to drink 
Drinking out of control
Increased tolerance
Withdrawal symptoms 
Little interest in anything else 
Drinking despite knowing dangers
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11
Q

Investigations

A
Ask about use who what where why when 
Level of dependency 
Alcohol related problems and other drug abuse 
Readiness or believe to change
PMH and physical health

Blood tests
Exclude anaemia and look st liver function and coagulation
Fasting. Glucose as chronic pancreatitis can lead to diabetes
Mcv raised and playlets low

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12
Q

Treatment

First Lin e

A
Support groups 
Counselling 
Rehab 
1:1 therapy 
CBT
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13
Q

Most effective

A

Abstinence

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14
Q

MedicFions which can be given to support

A
Pentoxifyline 
ChlordaPoxide 
Pabrinex 
Benzodiazepines 
Beta blockers 
Disulfram 
Acamprosate
Naltrexone
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15
Q

What is pabrinex

A

Vitamin b complex

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16
Q

Disulfram

A

It works to inhibit ALDH to enable acetylaldehyde to accumulate

17
Q

Which are used after successful withdrawal and mechanisms

A

AcMprosate

Naltrexone

Mechanisms are

Block gaba and nmda receptors to reduce cravings

Competitive antagonist of opioids receptor making less pleasurable
effects from drinking used for bingdrinkers to avoid large quantities

18
Q

Which two benzodiazepines are used and what for ?

A

Diazepam
LoraZepam

For reducing tremor and agitation
Reducing seizures