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BNF Chapter 2 - Cardiology > DOAC Doses > Flashcards

DOAC Doses Flashcards

1
Q

What is the usual dose for apixaban used in the treatment of AF?

A

5mg BD.

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2
Q

What is the dose of apixaban used in the treatment of AF when CrCl is between 15-29mL/min?

A

2.5mg BD.

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3
Q

What is the dose of apixaban used in the treatment of AF when the patient has 2+ comorbidities? (Age > 80, weight < 60kg, serum Cr > 133 micromol/L).

A

2.5mg BD.

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4
Q

What is the dose of apixaban used for the treatment of PE/DVT?

A

10mg BD for 7 days then 5mg BD.

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5
Q

What is the dose of apixaban used for the prevention of DVT/PE after 6 months treatment?

A

2.5mg BD.

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6
Q

What is the dose usual dose of edoxaban used in the treatment of AF?

A

60mg OD.

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7
Q

What is the dose of edoxaban used in the treatment of AF when the patient has 1+ comorbidities? (CrCl 15-50 mL/min, weight < 60kg, concurrent: ciclosporin, dronedranone, erythromycin, ketoconazole).

A

30mg OD.

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8
Q

What is the dose of edoxaban used for the treatment of DVT/PE?

A

60mg OD following parenteral anticoagulant for at least 5 days.

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9
Q

What is the dose of dabigatran used in the treatment of AF in patients <80 years old?

A

150mg BD.

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10
Q

What is the dose of dabigatran used in the treatment of AF in patients >80 years old or taking verapamil?

A

110mg BD.

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11
Q

What is the usual dose of dabigatran used in the treatment of DVT/PE?

A

150mg BD following parenteral anticoagulant for at least 5 days.

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12
Q

What is the dose of dabigatran used in the treatment of DVT/PE in patients >80 years old?

A

110mg BD.

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13
Q

What is the usual dose of rivaroxaban used in the treatment of AF?

A

20mg OD.

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14
Q

What is the dose of rivaroxaban used in the treatment of AF in patients with a CrCl of 15-49mL/min?

A

15mg OD.

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15
Q

What is the usual dose of rivaroxaban used in the treatment of DVT/PE?

A

15mg BD for 21 days then 20mg daily (minimum 3 months).

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16
Q

What is the usual dose of rivaroxaban used in the treatment of DVT/PE in patients with CrCl of 15-49mL/min?

A

15mg BD for 12 days and then 20mg OD. Or 15mg OD if bleeding risk > risk of DVT/PE.

17
Q

What is the dose of rivaroxaban used in the treatment of ACS?

A

2.5mg BD with aspirin alone OR aspirin and clopidogrel. Caution if >75 years or weight <60kg.

BNF Chapter 2 - Cardiology (10 decks)

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