dna virusis Flashcards

1
Q

icosahedral

A

Hepadnaviridae
Herpesviridae

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2
Q

Complex

A

Poxviridae

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3
Q

Hepadnaviridae
Herpesviridae
Poxviridae

A

DNA Enveloped Virus

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4
Q

Papillomaviridae
Polyomaviridae
Adenoviridae
Anneloviridae

A

Icosahedral
and
DNA Naked Virus

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5
Q

double stranded DNA with single stranded region
causes diseases related to liver

A

Hepadnaviridae

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6
Q

Genus: Orthohepadnavirus
causes Hepatitis B
with DANE particle (virion)
* HBsAg – surface antigen –outer membrane
* HBcAg – core antigen – surrounds the DNA
* HBeAg – components of the core antigen

A

Hepatitis B Virus

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7
Q

surface antigen –outer membrane

A

HBsAg

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8
Q

core antigen – surrounds the DNA

A

HBcAg

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9
Q

components of the core antigen

A

HBeAg

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10
Q
A
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11
Q

Modes of Transmission:
* Sexual contact
* Blood transfusion
* Inoculation of
contaminated secretions

A

Hepatitis B Virus

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12
Q

HBV Serological Markers

A
  • HBsAg – present in acute & chronic infection
  • Anti-HBs – indicates recovery or immunity
  • Anti-HBc IgM – present in acute (<6 months) infection
  • Anti-HBc – previous or ongoing infection
  • HBeAg – virus is replicating/ high levels
  • Anti-HBe – indicates lower level of HBV
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13
Q

Double stranded DNA
Causes lytic infection and latent infection
Remain in WBC & peripheral nerves
Replicate in nucleus

A

HERPESVIRIDAE

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14
Q

Genus: Simplexvirus
causes
* Oral Herpes – Gingivostomatitis
* HSV Encephalitis (adult)
* Ocular Herpes – Keratoconjunctivitis

A

Herpes-Simplex Virus 1

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15
Q

Genus: Simplexvirus
causes
* Genital Herpes
* Neonatal Herpes
* HSV Encephalitis (neonates)

A

Herpes-Simplex Virus 2

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16
Q

Mode of Transmission
* Contact with contaminated secretions
*Skin to skin contact
*Transmission between discordant partners

A

HERPESVIRIDAE

17
Q

Laboratory Diagnosis of HERPESVIRIDAE

A
  • Electron Microscope
  • Pap’s Smear
  • Dark Fluorescence Microscopy
  • Indirect Fluorescence
  • Culture
18
Q

Genus: Varicellovirus
causes
* Chickenpox
* Shingles (recurrent form)

A

Varicella-Zoster Virus (VZV or HHV-3)

19
Q

Mode of Transmission
* Droplet inhalation or respiratory droplets
* Direct contact with infectious lesions

A

Varicella-Zoster Virus (VZV or HHV-3)

20
Q

Laboratory Diagnosis
*Clinical signs
*Tzanck Smear

A

Varicella-Zoster Virus (VZV or HHV-3)

21
Q

Genus: Lymphocryptovirus
causes: Infectious
Mononucleosis (Kissing disease)
* Produce tumors
* Associated with Burkitt’s
Lymphoma and other B-cell
Lymphoma

A

Epstein-Barr Virus (EBV or HHV-4)

22
Q

Laboratory Diagnosis
* Hematology – differential smear
Immunology:
* Heterophil Antibody test
* Monospot test
*EBV Specific Antibody test
* not isolated in culture

A

Epstein-Barr Virus (EBV or HHV-4)

23
Q

EBV Specific Antibody Tests

Viral capsid antigen

A

Anti-VCA

24
Q

EBV Specific Antibody Tests

A
25
Q

EBV Specific Antibody Tests

A
26
Q

EBV Specific Antibody Tests

A