DNA viruses

Question 1

Tzanck prep revealing multinucleated cells

what virus

Answer 1

HSV-2

160

Question 2

fever, headache, rash with vesicles occuring and erupting over trunk and face

Answer 2

varicella (chicken pox) HHV 3, one of the herpes viruses

m287, 159

Question 3

keratoconjunctivitis

Answer 3

159
HSV-1
MCC of corneal blindness in US

Question 4

retinitis, owl eye inclusions, mononucleosis, monospot is negative what virsu

Answer 4

CMV, 158, 159, m 288

Question 5

how does EBV infect b cells

what lymphoma assocated

Answer 5

via CD21
Hodgkin and Burkitt lymphoma
159, 400

Question 6

child has high fever for several days, gets seizures, diffuse macular rash over chest

Answer 6

roseola; exanthem subitum; HHV6

158, 159, 176

Question 7

child with fever develops rash on face that spreads to body

Answer 7

B19, parvovirus

159, 176

Question 8

flesh colored papule with central umbilication

Answer 8

molluscum contagiousm
small pox, pox virus
158, m 294

Question 9

progressive multifocal encephalopathy in patient with HIV

Answer 9

polyomavirus: JC virus
158, 170
Junky Cerebrum

Question 10

kidney disease in renal transplant patient

Answer 10

Polyomavirus: BK virus

158

Question 11

transient aplastic anemia crisis

Answer 11

Parvovirus : B19

393, 158

Question 12

high fever, jaundice, black vomitus, nausea,

i. virus
ii. vector

Answer 12

i. flavivirus (flavi means yellow)
ii. Aedes mosquito
162

Question 13

fever, postauricular lymphadenopathy, arthralgies, fine rash in child

i. virus
ii. capsid symmetry

Answer 13

i. togavirus: Rubella
ii. icosahedral
163, 176

Question 14

break bone fever;

fever, back ache, headache

Answer 14

Dengue fever;
Flavivirus
161, m309

Question 15

destruction of anterior horns causing flaccid paralysis

Answer 15

poliomyelitis caused by : picornavirus: enterovirus: poliovirus
162, 471
fecal oral transmission

Question 16

hemorrhagic fever

Answer 16

filovirus: ebola vs Bunyavirus: hantavirus

161

Question 17

mouth blisters, fever, sore throat

i. virus

Answer 17

picornavirus: enterovirdiae: Coxsackievirus
herpangina
161,

Question 18

acute pericarditis caused by virus

Answer 18

coxsackievirus; 161, 299

Question 19

1 cause of fatal diarrhea in children

Answer 19

reovirus: rotavirus

161

Question 20

incubation period weeks to months; 
fever, malaise, agitation and hypersalivation; after bat bites
i. virus
ii. shape of virus
iii. what is seen in brain stem
iv. histo slide of neuron

Answer 20

i. rabies (rhabdovirus) 161
ii. bullet shaped
iii. brain stem encephalitis, unable to swallow resulting in foaming of mouth
iv. negri body: collections of virions in cytoplasm where replication occurs
165, m 312

Question 21

how does rabies virus get into the CNS

Answer 21

travels retrograde after binding to ACh receptors

165; 161

Question 22

enveloped, neg ssRNA virus with 8 segment genome

Answer 22

influenza virus; orthomyxovirus

163

Question 23

influenza like symptoms, viral menginitis

virus is envloped, ss 2 segments, helical capsid

Answer 23

LCMV lymphocytic choriomenginitis virus
Arenavirus
161

Question 24

febrile pharyngitis, acute hemorrhagic cystitis, conjunctivitis (pink eye)

Answer 24

Adenovirus; no envelope (naked)
DS and linear DNA
158
157

Question 25

what’s the only DS RNA virus?

Answer 25

reovirus; rota virus
157, 161
diarrhea

Question 26

what’s the only ssDNA virus?

Answer 26

parvovirus; 157, 158

‘part of a virus’

Question 27

where do DNA viruses replicate?

which one is exception

Answer 27

in nucleus except pox

157