DNA Virus Family: Poxviridae (1&2) - L16

Question 1

Poxviruses are DNA viruses, and therefore, predominantly replicate in the nucleus of host cells.

True or False ?

Answer 1

False

Note: Although it is a DNA virus it tends to replicate in the cytoplasm. The reason is, it has the information for synthesizing most of the enzymes required for its own replication process.

Question 2

Enveloped poxviruses are very fragile in the environment.

True or False ?

Answer 2

False

Question 3

Cowpox causes disease in which one of the following species ?

A. Cows
B. Humans
C. Cats
D. All of the above

Answer 3

D. All of the above

Note: The reservoirs are rats

Question 4

Pseudocowpox is zoonotic

True or False ?

Answer 4

True

Question 5

Orf is caused by:

A. Orthopxviruses
B. Parapoxviruses

Answer 5

B. Parapoxviruses

Question 6

It is recommended NOT to use a vaccine on a farm that does not have a problem with Orf.

True or False ?

Answer 6

True

Note: Should only be used in farms where there is a previous history of Orf or if that area or adjacent farms are endemic to Orf.

Question 7

In endemic areas, pregnant ewes should NOT be vaccinated against Orf

True or False ?

Answer 7

False

Note: Pregnant animals are vaccinated but the timing is normally 7-8 weeks before lambing

Question 8

Sheeppx and Goatpox cannot be distinguished from each other with serological techniques

True or False ?

Answer 8

True

Note: But genetically they are different viruses

Question 9

Sheeppox virus is commonly transmitted by ____

A. Mechanical transmission by arthropods
B. Aerosol route
C. Skin injury
D. Direct contact with contaminated objects

Answer 9

B. Aerosol route

Note: Droplet infection or through the respiratory tract. The virus can also be transmitted through other routes; but the most common route is aerosol route

Question 10

In sheeppox, pox lesions appear only on the skin.

True or False ?

Answer 10

False

Note: They appear on the skin but also can be seen in the GI Tract, respiratory tract, the reproductive tract, and urinary tract.

Question 11

Which one of the following plays an important role in transmission of swinepox virus ?

A. Ticks
B. Lice
C. Flies
D. Mosquitoes

Answer 11

B. Lice

Note: Normally lesions in the digestive and respiratory tract are acquired by piglets who get the disease congenitally

Question 12

The Dry form of Aviopoxvirus is more fatal than the Wet form

True or False ?

Answer 12

False

Note: The Wet form is the one with high mortality; the dry form is associated with cutaneous lesions on the skin -> a low production of eggs and low mortality.

Question 13

Which one of the following is NOT a common clinical lesion associated with Ulcerative Dermatosis of Sheep

A. Ulceration of vulva
B. Ulceration in leg
C. Ulcers in penis
D. Ulcers in pharynx

Answer 13

D. Ulcers in pharynx

Note: This disease has two forms: 1) The Lip and Leg ulceration form AND 2) Venereal form (in vulva and penis)

Question 14

What type of inclusion bodies would you encounter in host cells infected with pox virus?

A. Negri bodies
B. Owl’s eye bodies
C. Guarnieri bodies

Answer 14

C. Guarnieri bodies

Note: In Avipoxvirus you will get Bollinger and Borrel bodies in addition

Question 15

Which of the following poxviruses do not multiply in chicken embryo ?

A. Orthopoxviruses
B. Parapoxviruses
C. Capripoxvirus
D. Avipoxvirus

Answer 15

B. Parapoxviruses