DNA virus Flashcards

1
Q

Poxviridae
Classification

A
  • Enveloped (+/-) DNA viruses
  • Complex symmetry
  • Double stranded, linear
  • No. capsomers: -
  • Diameter 250x300nm
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2
Q

Family Poxviridae
subfamilies/genus/types species

A

Subfamily: Chordopoxvirinae
Produce proliferative focal skin lesions. Zoonotic potential
* Orthopoxvirus:
-vaccina virus, cow poxvirus
-variola virus
-simian poxvirus
* Parapoxvirus:
-papular bovine stomatitis virus
-orf virus - contagious pustular dermatitis (small ruminants)
* Avipoxvirus: fowl poxvirus
* Capripoxvirus: sheep and goat poxvirus
* Leporipoxvirus: myxoma (pox) virus of rabbits
* Suipoxvirus: swinepox virus
* Cervidpoxvirus: deer poxvirus
* Molluscipoxvirus: molluscum contagiosum virus
* Yatapoxvirus: Yaba monkey tumor virus

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3
Q

Iridoviridae
Classification

A
  • Enveloped (+/-) DNA virus
  • Icosahedral symmetry
  • double stranded, linear
  • No. capsomers: 1892
  • Diameter: 120-350nm
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4
Q

Family Iridoviridae
genus/types species

A
  • Ranavirus - Frog virus 3
  • Lymphocystivirus - lymphocystis disease virus 1
  • Megalocystivirus - Infectious spleen and kidney necrosis virus

Not known human pathogens

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5
Q

Asfaviridae
Classification

A
  • Enveloped DNA viruses
  • Icosahedral symmetry
  • Double stranded, linear
  • No. capsomers: (more or equal to) 1892
  • Diameter: 175-215nm
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6
Q

Family Asfaviridae
genus/types species

A
  • Asfivirus - African swine fever virus (ASFV)
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7
Q

Order Herpesvirales
Families

A
  • Herpesviridae
  • Adenoviridae
  • Papilomaviridae
  • Polyomaviridae
  • Hepadnaviridae
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8
Q

Herpesviridae
Classification

A
  • Enveloped DNA virus
  • Icosahedral symmetry
  • Double stranded, linear
  • No. capsomers: 162
  • Diameter: 125nm
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9
Q

Family Herpesviridae
Subfamilies/genus/types species

A

Important diseases of the skin, respiratory, intestinal, reproductive and nervous system. Persistent infections. cross the placenta

Subfamily: ALPHAHERPESVIRINAE
* Simplexvirus: Human herpesvirus 1 (oral), 2 (genital)
* Iltovirus: Gallid herpesvirus 1 - infectious laringotracheitis of chickens (ILT)
* Mardivirus: Gallid herpesvirus 2 - Marek´s disease of chickens
* Varicellovirus:
-Human herpesvirus 3 (varicella zoster)
-Porcine herpesvirus 1 - Aujesky´s disease (pseudorabies)
-Equine herpesvirus 1 - abortions, respiratory, neurological disease
-Equine herpesvirus 3 - veneral infections, coital exanthema
-Equine herpesvirus 4 - rhinopneumonitis, aborts
-Canine herpesvirus 1 - fatal generalized infection in pups
-Feline herpesvirus 1 - feline viral rhinotracheitis
-Anatid herpesvirus 1 - duck plauge
* VIRUSES:
-Bovine herpesvirus 1 - infectious bovine rhinotracheitis (IBR)
-Bovine herpesvirus 2 - bovine mammilitis
-Bovine herpesvirus 5 - encephalitis of calves

Subfamily BETAHERPESVIRINAE
* Cytomegalovirus: Human herpesvirus 5, cytomegalovirus - intrauterine infections (cause fatalities in neonates)
* Muromegalovirus: Mouse cytomegalovirus 1
* Proboscivirus: Elephantid herpesvirus 1
* Roseolovirus: Human herpesvirus 6
* VIRUS: Porcine herpesvirus 2 - inclusion body rhinitis in young animals

Subfamily GAMMAHERPESVIRINAE
* Rhadinovirus: Saimiriine herpesvirus 2
* Macavirus: alcelaphine herpesvirus 1 - bovine malignant catarrhal fever
* Percavirus: Equid herpesvirus 2, Equine herpesvirus 2, 5 - equine gammaherpesvirus infections
* Lymphocryptovirus: lymphoproliferative changes, malignancies
-Epstein-Barr virus (EBV) - infections mononucleosis of man
-Human herpesvirus 4

Order: Herpesvirales

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10
Q

Parvoviridae
Classification

A
  • Non-enveloped DNA viruses
  • Icosahedral symmetry
  • Single stranded, (-), linear
  • No. capsomers: 32
  • Diameter: 25nm
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11
Q

Family Parvoviridae
subfamily/genus/types species/
VIRUSES

A

Subfamily: Parvovirinae
Intrauterine infections
* Protoparvovirus: Minute virus of mice
* Erythoparvovirus: Human B19 virus
* Dependoparvovirus: Adeno-associated virus 2
* Amdoparvovirus: Amdoparvovirus carnivora 1 - aleutian mink disease virus (Minks) - chronic progressive, aleutian disease of homozygote minks, production of immunocomplexes - glomerulonefritis
* Bocaparvovirus: Bocaparvovirus 1, bovine parvovirus (bovine) - gastroenteritis - diarrhoea in calves

Viruses - host and infection
* Mink enteritis virus - Minks - generalized infection of minks analogical to feline panleukopenia
* Porcine parvovirus - pigs - main cause of Stillbirth+Mummification+Embryonic Death+Infertility
* Goos parvovirus - goos - highly contagious fatal disease - hepatitis, myocarditis
* Feline panleukopenia virus - cats - mainly in young animals, intrauterine infection, highly contagious systemic or intestinal infection, panleukopenia
* Canine parvovirus 2 - dogs - (parvovirus of dogs) highly contagious systemic or intestinal infection, intrauterine infection, immunosuppression, in puppies often fatal myocarditis

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12
Q

Adenoviridae
Classification

A
  • Non-enveloped DNA viruses
  • Icosahedral symmetry
  • Double stranded, linear
  • No. capsomers: 252
  • Diameter: 80-100nm
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13
Q

Family Adenoviridae
Genus/types species/disease

A

Rhinoparyngitis, (kerato)conjunctivitis, pneumonia, hepatitis, gastroenteritis
* Mastadenovirus:
-Canine adenovirus 1 (CAV1) - infectious canine hepatits (ICH), peracute or acute fatal disease, production of immunocomplexes
-Canine adenovirus 2 (CAV2) - infectious canine laringotracheitis (ICL) (kennel cough)
-Human adenovirus C
* Aviadenovirus:
-Fowl adenovirus A
-Atadenovirus A of poultry 1-11- hydropericard syndrome, inclusion hepatitis
* Atadenovirus:
-Atadenovirus 1 (AAV1) (Egg drop syndrome virus) - egg drop syndrome (EDS), shoft-shelled and shell-less eggs by apparently helathy chickens
-Ovine adenovirus D
* Siadenovirus:
-Frog adenovirus
-Phesant adenovirus - marble spleen disease, pulmonary odema, necrotic foci in spleens
-Turkey hemorrhagic enteritis virus - hemorrhagic enteritis, dysentery 4-12 weeks birds, high mortality, immunosuppresion

order: Herpesvirales

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14
Q

Papilomaviridae
Classification

A
  • Non-enveloped DNA viruses
  • Icosahedral symmetry
  • Double stranded, circular
  • No. capsomers: 72
  • Diameter: 45-55nm
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15
Q

Family Papillomaviridae
subfamilies/genus/types species

A

Subfamily: Firstpapillomavirinae
Proliferation of epithelial cells, mainly squamous, induce benign (cutaneous papiloma) or malignant tumours (carcinoma of cervix uteri)

  • Alpha-, Beta-, Gamma-, Mupa-, Nupa-, Omikron-papillomavirus: human papillomavirus
  • Eta-, Theta-papillomavirus: papillomavirus of some bird species
  • Iotapapillomavirus: rat papilomavirus
  • Deltapapillomavirus: european elk papilomavirus 1
  • Epsilonpapillomavirus: bovine papilomavirus 5
  • Kappapapillomavirus: cottontail rabbit papilomavirus
  • Lambdapapillomavirus: canine oral papilomavirus
  • Pipapillomavirus: hamster oral papilomavirus 3
  • Xipapillomavirus: bovine papilomavirus 3
  • Zetapapillomavirus: equine papilomavirus 1

order: Herpesvirales

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16
Q

Anelloviridae
Classification

A
  • Non-enveloped DNA viruses
  • Icosahedral symmetry
  • Single stranded, (-), circular
  • No. capsomers: 32?
  • Diameter: 20nm
17
Q

Family Anelloviridae
genus/type species

A
  • Alphatorquevirus: torque teno virus (TTV)
  • Beta-, Delta-, Epsilon-, Gamma-, Iota-, Theta-, Zeta-torquevirus: Anelovirus of man, primates, cats, dogs, pigs…
  • Gyrovirus: chicken anaemia virus (CAV)
18
Q

Circoviridae
Classification

A
  • Non-enveloped DNA viruses
  • Icosahedral symmetry
  • Single stranded, (+), circular
  • No. capsomers: 32?
  • Diameter: 17-22nm
19
Q

Family Circoviridae
genus/types species

A
  • Circovirus:
    -Psittacine beak and feather disease
    -Porcine circovirus 1 (PCV1)(apatogenic)
    -Porcine circovirus 2 (PCV2) - causal agent of post-weaning multisystemic wasting syndrome (PMWS) of pigs
20
Q

Hepadnaviridae
Classification

A
  • Enveloped DNA viruses
  • Icosahedral symmetry
  • Double stranded, circular
  • No. capsomers: ?
  • Diameter: 42-50 (40) nm
21
Q

Family Hepadnaviridae
genus/types species

A
  • Orthohepadnavirus: hepatitis B virus - cirrhosis of liver, hepatocellular carcinoma
  • Avihepadnavirus: duck hepatitis B virus

order: Herpesvirales

22
Q

Polyomaviridae
Classification

A
  • Non-enveloped DNA viruses
  • Icosahedral symmetry
  • Double stranded, circular
  • No. capsomers: 72
  • Diameter: 45-55nm
23
Q

Family Polyomaviridae
genus/types species

A
  • Betapolyomavirus: simian virus 40
  • Polyomavirus: polyoma, leukoencephalopathy, oncotic potential - different animals, cattle, birds and man

order: Herpesvirales