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Virology (Finals) > DNA Virus > Flashcards

DNA Virus Flashcards

1
Q

Pathogenic to human with grape-like cluster with cytopathic effect in cell culture

A

adenovirus (mastadenovirus)

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2
Q

ADENOVIRUS
- common manifestion:
- acquired thru contimated respiratory _, _ and _;
- replicates in _

A

Respiratory and gastrointestinal;
droplets, stool, formites;
oropharynx

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3
Q

ADENOVIRUS
has _ serotypes

Serotype 3 and 7 –
Serotype 4 and 7 –
Serotype 8 –
Serotypes 40 and 41 –

A

52

Pharyngitis
Respiratory disease epidemic in military
Conjunctivitis
Gastroenteritis in children

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4
Q

The only DNA hepatitis;

Associated with acute hepatitis but may lead to cirrhosis

A

Hepadnavirus

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5
Q

HEPADNAVIRUS
- only source of virus:
- infectious unit:

A

Humans
Dane particle or Australia antigen

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6
Q

Hepatitis
MOT: Fecal oral
Virus (ssRNA): Picornaviridae

A

HAV

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7
Q

Hepatitis
MOT: sexual, perinatal, parental
Virus: dsDNA (Hepadnaviri dae)

A

HBV

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8
Q

Hepatitis
MOT: sharing of needles
Virus (ssRNA): Flaviviridae

A

HCV

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9
Q

Hepatitis
MOT: Intravenous drug use
Virus (ssRNA): Delta virus

A

HDV

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10
Q

Hepatitis
MOT: Fecal oral
Virus (ssRNA): Hepevirus (under Calcivirus)

A

HEV

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11
Q

Hepatitis with fecal oral MOT

A

HAV
HEV

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12
Q

Creep, presence of ulcerative lesions; Large (150-200nm)
Lifelong persistence in their host

A

herpes virus

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13
Q

Herpes virus consists of 4 components:

A

“CENT”

capsid,
envelope
nucleic acid core
tegument,

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14
Q

defined as a condition already existing but not yet active or may not cause symptoms yet

A

latency

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15
Q

Herpes Virus

Spread by direct contact with infected secretions; Recurrence of skin lesion after primary infection

A

HSV-1 and HSV-2

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16
Q

HSV-1 and HSV-2 latency

A

sensory nerve ganglia

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17
Q

HERPES VIRUS

leading cause of fatal sporadic encephalitis and corneal infection in the US.

Encephalitis in older children and adults

— other disease associated with this herpes virus

A

HSV-1
— Gingivostomatitis, Herpes labialis, Keratitis, pharyngitis, herpetic whitlow, encephalitis

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18
Q

Types Herpes Virus

A

HSV-1: Cold sores/ Fever blisters
HSV-2: Genital infection/ Genital Herpes
HHV-3: Varicella Zoster Virus (VZV)
HHV-4: Epstein Barr Virus (EBV)
HHV-5: Cytomegalovirus (CMV)
HHV-6 & HHV-7: Human Herpes Virus
HHV-8: Rhadinovirus

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19
Q

Herpes Virus

Transmitted through personal contact especially respiratory

Presence of skin rash with blisters that look like dewdrops on a rose petal

Latency:

A

Varicella Zoster Virus (VZV) / HHV-3

VZV latency is dorsal root ganglia

20
Q

Herpes Virus

Transmitted through saliva

Causative agent of infectious mononucleosis (Glandular fever),
Burkitt lymphoma and nasopharyngeal carcinoma

A

Epstein Barr Virus (EBV) or HHV-4

21
Q

Epstein Barr Virus (EBV) or HHV-4 is the causative agent of:

A

infectious mononucleosis (Glandular fever), Burkitt lymphoma and nasopharyngeal carcinoma

22
Q

Herpes Virus

Salivary gland virus with owl’s eyes appearance

Transmitted through close contact with secretions, blood
transfusion (WBC), organ transplant and transplacental

Latency:

A

Cytomegalovirus (CMV) or HHV-5

Latency: white blood cell and endothelial cell

23
Q

CMV is the most common cause of _ and _

A

viral mental retardation; congenital disease

24
Q

Herpes Virus

Beta herpes virus

Transmitted through respiratory secretions; almost all children
from age 2-3 years old

Latency:

A

Human Herpes virus (HHV-6 and HHV-7)

Latency: CD4 (T Helper Cell)

25
Q

Lymphotropic virus and Roseola (Exanthem subitum) – fever with
short rash

A

Human Herpes virus (HHV-6 and HHV-7)

26
Q

Herpes Virus

Gamma herpes virus
• Kaposi Sarcoma

A

Rhadinovirus (HHV-8)

27
Q

Cause warts and exhibit tropism in cutaneous and mucocutaneous

A

Papillomavirus

28
Q

Type of Papillomavirus

A

o HPV 1 – Plantar warts
o HPV 2and 4– Warts of the Hand
o HPV 6 and 11 – Genital warts
o HPV 5 and 8 – Epidermodysplasia verruciformis
o HPV 13 and 32 – Heck’s disease (Focal epithelial hyperplasia)
o HPV 16 and 18 – Condyloma acuminate
o HPV 16 – subset of cancer of oropharynx and penile cancer in men
HPV 41 and 42 – Genital warts

29
Q

Plantar Warts

A

HPV 1

30
Q

Warts of the Hand

A

HPV 2 and 4

31
Q

Genital Warts

A

HPV 6, 11, 41, 42

32
Q

Epidermodysplasia verruciformis

A

HPV 5 and 8

33
Q

Heck’s disease (Focal epithelial hyperplasia)

A

HPV 13 and 32

34
Q

Condyloma acuminate

A

HPV 16 and 18

35
Q

subset of cancer of oropharynx and penile cancer in men

A

HPV 16

36
Q

Parvo = means small; smallest DNA virus

• Viral replication sites are erythroid progenitor cells, adult bone marrow
and fetal liver

• With characteristics slapped cheek appearance

A

Parvovirus B19

37
Q

associated with Erythema infectiosum

A

Parvovirus B19

38
Q

POLYOMA VIRUS

Hemorrhagic cystitis;

latent state in kidney

A

BK virus / Polyoma virus hominis 1

39
Q

POLYOMA VIRUS

Progressive multifocal leukoencelopathy;

latent state in B lymphocyte

A

JC virus / Polyoma virus hominis 2

40
Q

POLYOMA VIRUS

associated with Merkel Cell Carcinoma

A

MC Virus

41
Q

Largest and most complex of all viruses

Oval or brick shape virus

A

Poxvirus

42
Q

POXVIRUS

_ — absent or virulence, used in smallpox vaccine; causes cowpox

A

Vaccinia

43
Q

POXVIRUS

causative agent of smallpox virus

A

Variola/Orthopoxvirus

44
Q

POXVIRUS

small, pink, popular wart-like benign
tumors of the skin or mucous membrane

A

Molluscum Contangiosum

45
Q

POXVIRUS

transmitted by direct contact with sheep in which nodules in hands may be seen

A

Orf virus

46
Q

Large dsDNA virus which is the causative agent of African Swine Flu (ASF)

Not transmissible to human but highly pathogenic to pigs (causes
hemorrhagic fever to them)

Known to be transmitted by arthropods (soft ticks)

A

Iridovirus

47
Q

nasopharyngeal carcinoma causative agent

A

HHV - 4 (Epstein)

Virology (Finals) (6 decks)

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