DNA Test Flashcards

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1
Q

What did Freidrich Miecher do and when?

A

1869 - Isolated the material inside the nucleus & called it nucleic acid

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2
Q

What did Phoebus Levene do and when?

A

1900’s - Studied nucleic acid, found 2 types of acids in the nucleus that differed by 1 sugar (DNA/RNA)

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3
Q

What did Frederick Griffith do and when?

A

1928 - Experimented with mice and 2 types of pneumonia & discovered the transforming principal.

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4
Q

What did Pheobus Levene incorrectly conclude?

A

That Nitrogen bases in a DNA molecule were found in equal parts.

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5
Q

What did Avery, Maclead, & Mccarty do and when?

A

1944 - Took Griffiths research after he died & found that DNA was the transforming principal.

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6
Q

What did Hershey & Chase do and when?

A

1952 - Did a blender experiment that proved that the DNA passed on to one cell from another is not the protein.

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7
Q

Chargaff’s rule

A

That nucleotide A-T/C-G are not in equal amounts in the DNA.
This creates variation within a species.

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8
Q

What is DNA’s sugar

A

Deoxyribose

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9
Q

What is RNA’s sugar

A

Ribose

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10
Q

What does antiparallel mean

A

The lines move in opposite directions from each other.

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11
Q

What direction does DNA synthesize in?

A

DNA is always synthesized in the 5’-to-3’ direction by adding new nucleotides when creating a new DNA model.

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12
Q

What is a human genome?

A

Entire set of genetic instructions found in a cell.

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13
Q

What are the 4 stages of DNA replication?

A

1) Initiation
2) Elongation
3) Termination
4) Proofreading

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14
Q

What is initiation in DNA Replication?

A

Start - Enzyme helicase unwinds a portion of the DNA helix.

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15
Q

What is Elongation in DNA Replication?

A

DNA polymerase adds many bases to make a new strand from the template

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16
Q

What is Termination in DNA Replication?

A

Stop - the code at the end of the original strand that codes for stop.
That’s how DNA knows to stop adding new bases.

17
Q

What is proof-reading in DNA Replication?

A

DNA polymerase goes back to check over it’s work to look for mistakes.

18
Q

How does DNA make protein?

A

MRNA goes to get the message from DNA and writes it down, than translates the code
Ribosomes & TRNA help to make the protein by transferring amino acids.

19
Q

What is a protein?

A

A string of amino acids.

20
Q

What are the kinds of mutations?

A

1) Genetic (can be passed on)
2) Non- genetic (cant be passed on)

21
Q

What are the types of mutations?

A

1) Point mutations
2) Chromosomal mutation

22
Q

Occurs on a particular point of the DNA strand.

A

Point mutation

23
Q

Occurs during division of the cell, you either gain an extra chromosome, one less chromosome, part of a chromosome missing, or chromosomes are duplicated.

A

Chromosomal mutation

24
Q

How many strands in a DNA molecule

A

2 linked strands

25
Q

How many strands in a RNA molecule

A

1 (single stranded)

26
Q

Where is DNA located in the cell

A

Nucleus & mitochondria

27
Q

Where is RNA located in the cell

A

Nucleus, cytoplasm, and ribosome