DNA Test Flashcards
What did Freidrich Miecher do and when?
1869 - Isolated the material inside the nucleus & called it nucleic acid
What did Phoebus Levene do and when?
1900’s - Studied nucleic acid, found 2 types of acids in the nucleus that differed by 1 sugar (DNA/RNA)
What did Frederick Griffith do and when?
1928 - Experimented with mice and 2 types of pneumonia & discovered the transforming principal.
What did Pheobus Levene incorrectly conclude?
That Nitrogen bases in a DNA molecule were found in equal parts.
What did Avery, Maclead, & Mccarty do and when?
1944 - Took Griffiths research after he died & found that DNA was the transforming principal.
What did Hershey & Chase do and when?
1952 - Did a blender experiment that proved that the DNA passed on to one cell from another is not the protein.
Chargaff’s rule
That nucleotide A-T/C-G are not in equal amounts in the DNA.
This creates variation within a species.
What is DNA’s sugar
Deoxyribose
What is RNA’s sugar
Ribose
What does antiparallel mean
The lines move in opposite directions from each other.
What direction does DNA synthesize in?
DNA is always synthesized in the 5’-to-3’ direction by adding new nucleotides when creating a new DNA model.
What is a human genome?
Entire set of genetic instructions found in a cell.
What are the 4 stages of DNA replication?
1) Initiation
2) Elongation
3) Termination
4) Proofreading
What is initiation in DNA Replication?
Start - Enzyme helicase unwinds a portion of the DNA helix.
What is Elongation in DNA Replication?
DNA polymerase adds many bases to make a new strand from the template