DNA structure, replications and mutations

Question 1

Who dicovered DNA?

Answer 1

Johann Friedrich Miescher
Mid 19th century
Called it nuclein

Question 2

How was DNA dicovered?

Answer 2

Feulgen dye showed that DNA was in the chromosomes.

Question 3

How was it shown that DNA was a vector of inheritance?

Answer 3

Bacterial transformation using a strain of virulent streptococcus pneumoniae to induce virulence in a non virulent strain of the bacteria.

Question 4

How was DNA structure discovered?

Answer 4

X-ray crystallography and molecular modelling.

Question 5

Who discovered the structure of DNA?

Answer 5

Rosalind Franklin and Maurice Wilkins

Question 6

What does each nucleotide consist of?

Answer 6

Deoxyribose sugar
Nitrogenous base
Phosphate group

Question 7

What are examples of purine bases?

Answer 7

Adenine and guanine

Question 8

What are examples of pyrimidine bases?

Answer 8

Thymine and cytosine and uracil

Question 9

What was Watson and Crick’s model?

Answer 9

Double stranded helix
A pairs with T with 2 hydrogen bonds
C pairs with G with 3 hydrogen bonds
Sugar-phosphate was on the outside of the helix
The bases are on the inside of the helix
The 2 strands are antiparallel