DNA Replication Flashcards
What is the term for the method of DNA replication where half of the strands in each new DNA molecule are from the original DNA molecule?
Semi-conservative replication
This method ensures that each new DNA molecule contains one original and one newly synthesized strand.
What enzyme is responsible for breaking hydrogen bonds between bases during DNA replication?
DNA helicase
This enzyme unwinds the DNA double helix to allow replication.
What is the role of DNA polymerase in DNA replication?
Catalyzes condensation reactions to join adjacent nucleotides
DNA polymerase also helps in forming hydrogen bonds between complementary bases.
What structure do DNA and RNA share as types of nucleic acids?
Polymer of nucleotides
Both consist of pentose sugar, nitrogenous bases, and a phosphate group.
Fill in the blank: DNA is structured as a _______ held by hydrogen bonds.
Double helix
This structure consists of two antiparallel strands.
What are the base pairs in DNA?
- Adenine - Thymine
- Cytosine - Guanine
These pairs are held together by hydrogen bonds.
What happens during the first step of DNA replication?
DNA untwists
This is facilitated by the enzyme DNA helicase breaking hydrogen bonds.
What is a mutation?
Changes in the genome that can occur during DNA replication
Mutations can lead to variations in genetic information.
List examples of DNA mutations.
- Substitution
- Deletion
- Addition
- Duplication
- Inversion
- Translocation
Each type of mutation alters the DNA sequence in different ways.
True or False: DNA replication is carefully controlled to preserve genetic information.
True
Despite this control, mutations can still occur.
What is the significance of polypeptides in relation to proteins?
They change tertiary structure
This change can impact the function of enzymes.
What must students do to complete the participation assessment worth 5%?
Complete every question of the quiz at the end of each lecture
Participation is mandatory, but correctness is not required.
Fill in the blank: If unable to attend the lecture for medical reasons, students must _______.
Email the instructor directly
This ensures proper communication regarding attendance.
What should students do if they do not have a mobile phone in the lecture?
Ask for a paper copy of the quiz at the START of the lecture
Failing to do so may result in being marked as non-participating.
What is the recommended reading for today’s lecture on DNA replication?
Pages 55-58 of the course material
Students should make notes from this reading.