DNA- Replication Flashcards
When does DNA- Replication happen?
before cell divison, during the interphase between Mitosis and Meiosis
What is DNA- Gyrase?
an enzyme that unwinds the double helix shape of DNA
What is DNA-Helicase?
an enzyme that splits up the hydrogen bonds between the bases and thus “unzips” the double helix
What are single-strand binding proteins?
small proteins that temorary bind to each side and keep the DNA strands separated
What is DNA-polymerase?
walks down the DNA from 5’ to 3’
adds new nucleotides to each strand, (nucleotides pair with the complementary one, A&T, G&C)
What is primase?
An enzyme that binds a primer to the DNA strand, so the DNA-polymerase knows where to start building small parts of the DNA-strand –> these parts are called Okazaki fragment
when primer removed: gaps
What are Okazaki fragments?
small parts of the DNA strand complemented by polymerase
What is ligase?
an enzyme sealing the gaps between the okazaki-fragments with nucleotides
what does semi-conservative replication mean?
the DNA molecule consists of a parent strand and a new strand
