DNA Repair Mechanisms Flashcards

1
Q

Polymerase proofreading

A

DNA polyermase while replicating has proofreading abilities to check

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2
Q

Direct Repair

A

repairs dimers by using DNA photolyase to fix pyrimidine dimer to break bond and absorb light

OR: using methylguanine methyltrasnferase to more the methyl from G–C when it doesn’t belong there

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3
Q

Base excision repair

A

replaces the wrong base, for non-ioninzing/non-distorting repairs uusing DNA Glycosylase

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4
Q

nucleotide exision repair

A

changes the entire nucleotide in distorting change using the NER complex

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5
Q

mismatch

A

fixes the mismatched pair in teh daughter cell, this is dangerous due to the misfolding of the DNA causing a deformity

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6
Q

recombination

A

breaks the double strand or inner strand caued by crosslinking by ionizing radiation

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7
Q

non-homologous end joining

A

cuts cross linking out and just puts them back together, could be missing DNA

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8
Q

homologous end joining

A

you have the template to fix and fill in

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9
Q

transcription coupled repair

A

will see RNA stalling and allow it to continue on

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