Antibiotics & Toxins Flashcards
1
Q
Streptomycin
A
prokaryotic- 30S (small subunit) disrupts START (initiation) interrupts binding the small and large subunit
Streptomycin Start Small
2
Q
clindamycin & erythromycin
A
prokaryotic- 50S
disrupts translocation of ribosome
3
Q
tetracyclin
A
prokaryotic- 30s
disrupts ELONGATION
4
Q
chloramPhenicol
A
prokaryotic- inhibits Peptidyl Transferase (can’t make Peptide bonds)
5
Q
Shiga toxin & ricin
A
eukaryotic- 60s disrupts Elongation
6
Q
Diphtheria
A
Eukaryotic -inactivates eEF2 elongation and translocation
mnemonic: DeEF-2
7
Q
Cyclohexamide
A
Eukaryotic: inhibits Petidyl Transferase
8
Q
Puromycin
A
both
TERMINATION