Antibiotics & Toxins Flashcards

1
Q

Streptomycin

A
prokaryotic- 30S (small subunit)
disrupts START (initiation) 
interrupts binding the small and large subunit 

Streptomycin Start Small

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2
Q

clindamycin & erythromycin

A

prokaryotic- 50S

disrupts translocation of ribosome

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3
Q

tetracyclin

A

prokaryotic- 30s

disrupts ELONGATION

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4
Q

chloramPhenicol

A

prokaryotic- inhibits Peptidyl Transferase (can’t make Peptide bonds)

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5
Q

Shiga toxin & ricin

A

eukaryotic- 60s disrupts Elongation

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6
Q

Diphtheria

A

Eukaryotic -inactivates eEF2 elongation and translocation

mnemonic: DeEF-2

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7
Q

Cyclohexamide

A

Eukaryotic: inhibits Petidyl Transferase

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8
Q

Puromycin

A

both

TERMINATION

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