DNA, genes, cellular, reproduction and biotechnology lecture 4 Flashcards

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1
Q

What is Genetics?

A

the study of heredity

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2
Q

Who was founder of foundations of inheritance principles?

A

Mendel

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3
Q

What did Mendel do his experiments on

A

pea plants

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4
Q

What is hybridization?

A

-genetic material from both parent plants combined
Plants used in first - generation hybrids called P ( parental generation) plants
- Mendel collected the seeds from the P plants that resulted from each cross and grew them the next year
- Mendel noted characteristics of F1 plants and let them self fertilize naturally
- Mendel collected and grew the seeds from F1 to produce F2 plants

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5
Q

What were Mendel’s results from his

A

Mendel reported the results of his crosses involving seven different characteristics each with two contrasting traits

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6
Q

what is traits?

A

variation in the physical appearance of a heritable characteristic

Example: flower color: traits were white vs violet

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7
Q

What are dominant traits?

A

Those that are inherited unchanged in a hybridization

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8
Q

What is recessive traits?

A

Disappear in the offspring of a hybridization
- would reappear in the progeny of the hybrid offspring

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9
Q

Dominant vs recessive trait

A
  • physical observation of a dominant trait meant that organism had two violet genes ( two dominant versions), or one violet and one white gene( one dominant, one recessive)

-observation of a recessive trait meant that the organism had two white genes ( had no dominant versions for this characteristics

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10
Q

What are alleles? Provide example.

A

Are a gene variants that arise by mutation and exist at the same relative locations on homologous chromosomes

Example: one chromosome come from each parent
- genes for pea pods - allele for green vs yellow color

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11
Q

What is the difference between phenotype vs genotype? Provide an example for each one.

A

Phenotype is the observable traits in an organism
Example : yellow seed color in pea plants

Genotype: an organism’s underlying genetic makeup, consisting of both the physically visible and the non - visible alleles
Example: YY or Yy alleles for yellow seed color
- seeds appear equally yellow, even though alleles are different

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12
Q

What is the difference between homozygous and heterozygous? Provide example for each one.

A

Homozygous is the same copy of allele for specific gene
YY, yy
Heterozygous is different copies of allele for specific gene
Yy, yY

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13
Q

What is Mendel’s law of segregation ( first law) Provide example

A

states that genes must segregate equally into gametes such that offspring have an equal likelihood of inheriting either gene

Example: offspring equally likely to inherit y or Y gene from a Yy parent

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14
Q

What Mendel’s law of independent assortment (second law) Provide example

A

states that genes do not influence each other with regard to the sorting of alleles into gametes
- every possible combination of alleles for every gene is equally likely

Example: gene for seed color (Yy) acts independently from gene for seed shape (Rr)

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15
Q

What is Mendel’s law of dominance ( third law)

A

states that some alleles are dominant and others recessive
- Individuals will display the effects of only the dominant allele

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16
Q

What are Human discontinuous traits?

A

albanism vs non - albinism
- both parents are non - albinos ( A phenotype) but carry allele for albinism
- parents both have Aa genotype
- albino child has aa genotype
- two albinos always produce albino children

  • Red hair/freckles, cystic fibrosis, huntington’s disease, hemophilia
17
Q

What is PTC?

A

dominant gene for ability to taste bitter chemical
- bitter chemical is tasteless for those with recessive genes

18
Q

What is incomplete dominance? Provide examples.

A

One of the alleles appears in the phenotype in the heterozygote, but not to the exclusion of the other, which can also be seen

Example: color in snapdragons ( red dominant, white recessive)

19
Q

What is Co- dominance? Provide example

A

some discontinuous traits can have two dominant states, which are equally expressed when present
- both alleles for the same characteristic are simultaneously expressed in the heterozygote

Example: human blood group (A, B, O alleles)
O is recessive ( A and B are co - dominant)

20
Q

What is polygenic trait? Provide example.

A

more than 2 alleles and multiple genes work together additively to produce a phenotype

Example: eye color ( light - dark) controlled by at least 8 genes

21
Q

What is epistasis? Provide example.

A

when the presence of one gene masks or interferes with the expression of the other

Example: coat pigment in mice