DNA and the Gene: Synthesis and Repair

Question 1

Replisome

Answer 1

A large macromolecular machine

Question 2

Helicase

Answer 2

Catalyzes the breaking of hydrogen bonds between base pairs to open the double helix

Question 3

Single strand DNA binding proteins (SSBP)

Answer 3

Stabilizes single-stranded DNA

Question 4

Topoisomerase

Answer 4

Brakes and rejoins DNA double helix to relieve twisting forces caused by the opening of DNA

Question 5

Sliding clamp

Answer 5

holds DNA polymerase in place during strand extension

Question 6

Telemere

Answer 6

Reion at the end of a eukaryotic chromosome

Question 7

Telomerase

Answer 7

adds more repeating bases to the end of the lagging strand, catalyzing the synthesis of DNA from an RNA template that it carries with it.

Question 8

Hayflick Limit

Answer 8

Cells can only divide about 50x

Question 9

T-T Dimer

Answer 9

UV radiation causes DNA to have T bonded to T - causes kink in DNA

Question 10

nucleoide excision repair

Answer 10

Repairs T-T dimers by removing section of DNA and resynthesizing it