DNA and pRotein Synthesis Flashcards
DNA double helix discovered in?
1953
What are the three major functions of DNA?
Controlling cellular activities
Making exact copies of itself ( DNA replication)
Undergoing mutations
What is a polymer of nucleotide
Means many (large molecule of many sub molecules (nucleotide)
Each nucleotide is composed of?
Pentose (5 carbon sugar)
Phosphate
Nitrogenous base
What are the two types of bases?
Purines , pyrimidines
Purines-
Have a double ring structure
Adenine and guanine
Pyrimidines-
Have a single ring structure
Thymine and cytosine
Uracil replaces what in what?
In RNA , replaces thymine
Each strand of DNA or one side of the ladder is composed of a back bone of alternating molecules, what are they?
Deoxyribose, phosphate, nitrogenous base
Adenine bonds with ______ and has____ hydrogen bonds
Thymine and has two hydrogen bonds
Guanine bonds with _____ and has ____hydrogen bonds
Cytosine and 3 hydrogen bonds
What is chargaffs rule?
Number of purine bases equals number of pyramidine bases
Genes are located on the
Chromosome
If a chromosome is like a cook book a. Gene is like___
A recipe
A gene consists of a sequence of about ____dna base pairs
I1000
Genes always occur in ____
Pairs
Genes control_____
Cellular chemical reaction
In what structure are genes found?
Chromosomes
What bases are used in RNA
U A G C
What bases are used in DNA
A T G C
What is replication
Copying the DNA
What is transcription
Turning into messenger rRNA strand
What is translation
Create amino acid from RNA
What is semi conservative replication
Half and half
One new strand one old strand
What is the sugar in DNA?
Deribose
What is the sugar in RNA?
Ribose
RNA has how many strands
Single stranded
DNA has how many strands
2
What are the three types of RNA
Ribosomal (rRNA)
Messenger (mRNA)
Transfer (tRNA)
What is the function of rRNA?
Aid in protein synthesis - read mRNA codon
What is the function mRNA
Copying sections of DNA template strand
What is the function of tRNA
Carries the amino acid from the cytoplasm to a ribosome for protein synthesis
What does a polymerase-p do
Makes molecules
What is the sense strand?
Makes sense, is used
______for diabetic patients can be synthesized by bacteria that have undergone recombinant DNA processes
Insulin
The final phase of translation where the amino acid chain is released from the ribosomes
Termination
A gene mutation where a nucleotide is removed from a gene
Deletion
________bonds form between the nitrogenous bases in the DNA molecule
Hydrogen
Unlike DNA , RNA is a ____-stranded molecule
Single
The process of creating an mRNA strand from a DNA molecule
Transcription
The shape of the DNA molecule
Double helix
Something that can get DNA from one species into the cells of another species
Vector
Any factor which causes a mutation is called
Mutagen
A gene mutation where one nucleotide is replaced by a different nucleotide
Substitution
DNA and RNA are both
Nucleic Acids
If a DNA strand read gatggctca , the complimentary DNA strand would be
CtaccGaGt
This type of RNA is used in the ribosomes during protein synthesis
rRNA
The process of DNA making copies of itself
Replication
The first phase of translation where the mRNA and first tRNA join up with the small ribosomal subunit is called_____
Initiation
DNA is found in the ____ of the eukaryotic cells
Nucleus
Many ribosomes can be translating a single mRNA strand at the same time-this unit is called a
Poly some
The enzyme that adds nucleotides to the growing strand during transcription
RNA polymers
A nitrogenous base with a double ring structure
Purine
Proteins which associate with DNA to form chromosomes
Hi stones
The enzyme that unzips the DNA strand during replication
Helicase
A DNA subunit made up of three subunits
Nucleotide
A three letter sequence on tRNA that is complimentary to an mRNA condone
Anticodon
This type of RNA delivers amino acids to the ribosomes
tRNA
Chromosomal______occurs when entire portions of chromosome are removed
Deletions
A change to the base pair sequence of a DNA molecule
Mutation
A chromosomal mutation where a piece of chromosome is flipped
Inversion
Proteins are made up of chains of______strung together
Amino acids
This type of RNA brings the instructions from the DNA molecule to the ribosomes
mRNA
DNA is made up of many repeating subunits and is therefore referred to as being a
Polymer
Replication of the DNA molecule is concidered to be a ____process because each daughter strand contains half old DNA and half new
Semi conservative
The reading of an mRNA strand by a ribosome to make a protein is called ______
Translation
Uv lights and X-rays are an example of _______mutagens
Radiation
A____ mutatgen only affects one gene
Gene
Hpv is an example of a ____ mutagen
Viral
A gene mutation where a nucleotide is inserted into a gene
Addition
A chromosomal mutation where a piece if one chromosome is transferred to another chromosome
Translation
RNA contains one nitrogenous based not found in the DNA called____
Uricil
A nitrogenous base with a single ring structure
Pyramidine
Completed proteins are sent to the ______. For final packaging and processing
Golgi apparatus
Benzene and dioxins are examples of ___mutagens
Chemical
A chromosomal mutation where a portion of a chromosomes repeats itself
Duplication
A mutagen that causes cancer is called
Carcinogen
_____mutations occur in the gametes or early on in embryological development
Germinal
____bonds occur between joining amino acids
Peptide
The number of purines will always equal the number of pyramidine acording to ___ rule
Chargoffs
___base pairing means that only a with pair with t and only g will pair with c
Complimentary
The amino acid chain is released from the ribosome when a stop codon signals for a ____________ to enter the ribosome
Release factor
A small circular piece of DNA that can be used to transfer DNA from one species to another.
Plasmids
A _____ mutation affects many genes because a large portion of chromosomes are altered
Chromosomal
Addition and deletion mutagens can cause devastating effects because they cause a ________
Frame shift
The enzyme that adds new DNA nucleotides to the growing strand during replication
DNA polymers
The second phase of translation where the amino acid chain grows is called the______
Elongation
Strong______ bonds form between sugar and phosphates to form the backbone of the molecule
Convalent
The three letter sequence on mRNA that codes for an amino acid
Codons
____mutations occur in the cells after birth
Somatic