DNA Flashcards

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1
Q

What are the 3 components of a DNA structure?

A

A phosphate, a deoxyribose sugar and a base.

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2
Q

What is the difference between a Nucleoside and a Nucleotide?

A

A nucleoside contains a deoxyribose sugar and a base, whereas a nucleotide contains both of these plus a phosphate.

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3
Q

Name the bases and the pairs they form.

A

Adenine and Thymine & Cytosine and Guanine.

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4
Q

Which bases are purines?

A

Adenine and Guanine.

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5
Q

Which bases are pyrimidines?

A

Thymine and Cytosine.

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6
Q

When base pairs join, what type of bonds are formed?

A

Hydrogen bonds. 3 Hydrogen bonds between G & C and 2 Hydrogen bonds between A & T.

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7
Q

How are nucleosides formed?

A

Nucleosides are formed following a condensation reaction between a sugar and a purine or pyrimidine base, with the removal of water, forming an N-glycosidic bond (strong covalent bond).

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8
Q

How are nucleotides formed?

A

Nucleotides are formed following a further condensation reaction between the nucleoside and phosphoric acid. The bond formed is a phosphodiester bond, which is a strong covalent bond and stems from the elimination of another water molecule.

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9
Q

What is the full name for Deoxyribose?

A

Deoxyribonucleotides.

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10
Q

How is a phosphodiester bond formed?

A

A phosphodiester bond is formed when nucleotides are joined by covalent phosphoester bonds that are formed between the sugar of one nucleotide and the phosphate group of the next nucleotide.

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11
Q

In which way do opposite DNA strands run?

A

Anti parallel to each other, e.g. one strand is 5’ to 3’ direction and the other is 3’ to 5’ direction.

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12
Q

Where is DNA found within Prokaryotic cells?

A

Free within the cytoplasm.

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13
Q

Where is DNA found within Eukaryotic cells?

A

DNA exists in the form of chromosomes within a membrane-bound nucleus.

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