DNA Flashcards
virulent
strain of bacterium that causes disease
transformation
transfer of genetic material from one cell/organism to another
bacteriophage
virus that infect bacteria
virulent strain of bacterium S. pneumoniae causes disease because
it has a capsule
Hershey and Chase used what organism in their experiments
E. coli
Hershey & Chase’s experiment lead to the conclusion that
DNA is responsible for transformation in bacteria
purine
nitrogenous base with 2 rings
A
Adenine
G
Guanine
Pyrimidine
nitrogenous base with 1 ring
T
Thymine
C
Cytosine
DNA
deoxyribonucleic acid
complementary base pair
A + T, G+ C, connected by hydrogen bond
nitrogenous base
base containing nitrogen and oxygen
replication fork
y-shaped region that result when 2 parental strands separate
helicase
enzyme that separates parent strands
replication of a DNA strand happens in
two different directions
a mutation is a
change in the nucleotide sequence of DNA
which enzyme breaks the hydrogen bonds (separates parent strands)
helicase
initiation
helicase separates DNA strands
elongation
DNA polymerase makes complementary nucleotides
termination
polymerases released, 2 identical copies of parent strands
A and B form of DNA
A is dryer (produces detailed images)
B is wetter (produces simpler images)
x pattern means
helix shape
how many base pairs (units) are there in each full turn of the helix
10
how many hydrogen bonds do A and C have
2
how many hydrogen bonds do G and C have
3
3 components of a nucleotide
nitrogenous base, deoxyribose, phosphate group
chargaff
discovered that A=T, etc.
phosphate groups and deoxyribose sugar are held together by
covalent bonds
two DNA strands are
anti parallel
5’ end with
phosphate
3’ ends with
deoxyribose
what was thought to be the genetic blueprint orignally
proteins
enzymes that destroyed DNA
prevented transformation
space between separated strands
replication bubble
enzyme that checks for mistakes
proof reading enzyme
DNA travels in
5’ to 3’
bacterial transformation
griffith
base-pair rule
chargaff
DNA is the hereditary material of viruses
chase and hershey
shape of DNA is helix
franklin and wilkins
DNA is a double helix
watson and crick
how many replication bubbles are on each DNA molecule
multiple
leading strand
synthesized continuously
lagging strand
synthesized in pieces (okazaki fragments)
mutagen
agent that induces or increased the frequency of mutations