DMARDS Flashcards
Which anti-inflammatory agents can be taken orally
DMARD like methotrexate, and kinase inhibitors like tofactinib
How is methotrexate given?
Oral IM sub Q once a week
Which anti-inflammatory agent requires a folate supplement to be given with it
Methotrexate
How long do conventional DMARDS take to work?
Weeks to months
How long do biologic take to work?
2 to 6 weeks
What are the common side effects associated with the biologic enteracept
Lymphoma, impedes, diarrhea, rash, and upper respiratory infections
Which anti-inflammatory agents can you be used to treat psoriasis
Biologic and bio similars
Which anti-inflammatory agent can be used to treat felty syndrome
DMARDs methotrexate
Which inflammatory agents can be used to treat G.I. inflammatory diseases
Biosimilars like infliximab abbd
Which drugs can only be given parentally due to being large molecules
Biologic and bio similars
How are biologic designed
They are recombinant DNA protein products
How bio similar’s designed
There are reverse engineered copies of biologic
How are Kinases inhibitors designed?
They are synthetic DMARD
What class does adacept belong to?
It is a biologic of the T lymphocytes inhibitor class
What class does entanercept an infiximab belong to?
They are tumor necrosis factor inhibitors that are in the biologic class
What class does rituximab belong to?
Be lymphocyte antigens in the biologic’s class
What class does tociulizumab belong to?
Interleukins inhibitors of the biologic class
Which class is less expensive biologic or bios similar’s?
Bio similars
How are bios similar’s named
They are named after the product. They are engineered from followed by a four letter sequence like influximab abbd
What should you monitor in patients taking DMARDs
You should monitor GFR full eight levels and advise patients to avoid alcohol. If they cannot avoid alcohol you have to monitor LFTs.
How are kinase inhibitors administered?
Orally
Which drug is a synthetic DMARD
Kinase inhibitors like tofactinib
