DLE Flashcards
What is Discoid Lupus Erythematosus (DLE)?
DLE is an autoimmune chronic skin condition that primarily affects the skin and is more common in women, typically presenting between the ages of 20-50. It is more common in darker-skinned patients and smokers.
DLE is characterized by its chronic nature and specific demographic prevalence.
What is the association between Discoid Lupus Erythematosus (DLE) and systemic lupus erythematosus (SLE)?
DLE is associated with an increased risk of developing SLE, although the risk is below 5%.
This indicates a potential progression from a localized skin condition to a more systemic disease.
What rare complication can arise from Discoid Lupus Erythematosus (DLE)?
Rarely, the lesions of DLE can progress to squamous cell carcinoma (SCC) of the skin.
This highlights the importance of monitoring DLE lesions for any changes.
Where do lesions typically occur in Discoid Lupus Erythematosus (DLE)?
Lesions typically occur on the face, scalp, and ears.
These areas are particularly sensitive and visible, which can affect patient quality of life.
How are DLE lesions affected by sunlight?
DLE lesions are photosensitive, meaning they are made worse by exposure to sunlight.
Sunlight exposure can trigger or exacerbate symptoms.
What are the characteristic features of DLE lesions?
The lesions are inflamed, dry, erythematous (red), and scaling. They are associated with scarring alopecia (hair loss) and hyperpigmentation or hypopigmentation.
These features can help in differentiating DLE from other skin conditions.
What is used to confirm the diagnosis of Discoid Lupus Erythematosus (DLE)?
A skin biopsy can be used to confirm the diagnosis.
This diagnostic method provides histological evidence of the condition.
What is the management for Discoid Lupus Erythematosus (DLE)?
Management includes:
* Sun protection
* Topical steroids
* Intralesional steroid injections
* Hydroxychloroquine
These treatments aim to reduce inflammation and prevent further skin damage.
