DLA 14 Flashcards
What are the consequences of altering a nucleotide sequence?
nonsense mutation
silent mutation
missense mutation
What is the start codon?
AUG
What are stop codons?
UAA
UAG
UGA
what are the components required for translation?
mRNA
ribosomes
charged tRNA
GTP
initiation factors
What are the three binding sites of the ribosome?
P site
A site
E site
What does the P site do?
holds the tRNA that carries the growing chain
What does the A site do?
holds the tRNA that carries the next AA to be added
What does the E site do ?
the exit site
What are the prokaryotic subunits of the ribosome?
50S and 30S = 70S
What are the eukaryotic subunits of the ribosome?
60S and 40S = 80 S
The wobble hypothesis?
The first two bases of the codon are traditional, but the last base is less stringent