Divers Flashcards

1
Q

Principe de chimio pour LNH?

A

CHOP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Principe de tx de chimio pour LH?

A

ABVD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Principe de tx de chimio pour CCR?

A

folfiri
folfox
xelox

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

que signifie chimio intrathécale?

A

dans le SNC via PL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Vrai ou faux:

la majorité des tx de chimio ne pénètre pas la barrière hématoencéphalique (SNC)

A

vrai

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

E2 communs de chimio?

A

GI
no/vo, diarrhée, mucosite, perforation

Hémato
myélosuppression: granulocytopénie, thrombocytopénie, anémie

dermato
alopécie

SNC
vo étio central

SNP
PNP

sex
infertilité

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Tx support chimiotx?

A
prophylaxie infectio
support psycho
physiotx
tx occupationnelle
anti nauséeux
antidiarrhée
selon cas: bactrim, fluconazole
hydratation
allopurinol
prohématopoièse--> G-CSF ex. grastofil
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Comment dx SHU?

A
thrombopénie
anémie, schistocytes
LDH aug
possible contexte infectieux récent
IRA (ex. aug créat)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

rx pouvant prévenir la myélosuppression secondaire (entrainant fatigue, fièvre) à MTX (pour PAR par exemple)?

A

leucovorin (acide folique)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Quel le lien entre l’IRC et la FSC?

A

rein = érythropoïétine = utile pour érythropoïèse = formation de globule rouge

si IRC –> anémie par dim érythropoïétine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Gène associé à la LMC?

A

chromosome de philadelphie – BCR-ABL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q
Qui suis-je?
en lien avec sepsis / infection récente ou en cours
DEG
T
tachycardie
tachypnée
hypotension
pétéchies/ecchymoses
thrombopénie
temps de saignement (TCA) aug
créat aug
désordres ions
A

CIVD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

lymphome ayant association avec sida/vih et EBV?

A

lymphome cérébral primaire

LNH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

dx le plus prob:
anémie
sx vasocclusif aux mains (érythème, dlr, fièvre, oedème, chaleur)?

tx/prophylaxie?

A

anémie falciforme (sickle cell diease)

hydroxyurea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

agents chimio permettant de briser la double hélice de l’ADN afin de la scinder en un seul brin?

A

Topoisomérase I

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Quels sont les sd associés au néo du poumon à petites cellules?

A

SIADH (hyponatrémie)
Eaton-Lambert
Cushing

17
Q

comment reconnaitre anémie falciforme au frottis sanguin?

A

corps de Howell-Jolly (débris de noyau ds érythrocytes)

18
Q

cellules au frottis d’une LLC?

A

'’smudge cell’

Detection of B-CLL immunophenotype (CD19, CD20, CD23) in flow cytometry would further support the diagnosis.

19
Q

Qu’est-ce que GCSF? ou grastofil? ou filgratim?

A

Filgrastim is a recombinant granulocyte-colony stimulating factor that is commonly used to reduce the duration of chemotherapy-induced neutropenia. G-CSF stimulates common myeloid progenitor to become myeloblasts, and then further induces myeloblast to become either neutrophils or basophils. Unlike GM-CSF, which induces the differentiation of all myeloid leukocytes, G-CSF does not promote myeloblasts to differentiate into either monocytes or eosinophils.