diuretics and electrolytes Flashcards

1
Q

Carbonic anhydrase inhibitors

A
  • acetazolamide
  • methazolamide
  • dichlorophenamine
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2
Q

carbonic anhydrase inhibitors MOA

A
  • inhibits Ca which inhibits H+ secretion in the PCT
  • bicarb and Na are blocked from reabsorption
  • hypokalemic metabolic acidosis
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3
Q

osmotic diuretics

A
  • mannitol
  • urea
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4
Q

osmotic diuretics MOA

A
  • increase osmotic gradient in the PCT
  • decreased Na reabsorption = water follows
  • risk of hypernatremia
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5
Q

what ions are excreted with mannitol

A
  • water
  • Na
  • Cl-
  • HCO3
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6
Q

where does fluid move when mannitol is administered

A
  • draws fluid from intracellular to extracellular spaces
  • acutely expands intravascular volume
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