Diuretics Flashcards
0
Q
Location and mechanism of action of thiazide
A
DCT
Inhibit Na/Cl symport
1
Q
Location and mechanism of action of loop
A
Thick ascending limb
Inhibit Na/K/2Cl symport
2
Q
Location and mechanism of action of K sparing
A
DCT and CT
Inhibit ENaC
3
Q
Location and mechanism of action of aldosterone inhibitors
A
All
Reduce number of ENaC
4
Q
Which diuretics cause hypokalaemia and how
A
Loop and thiazide
Na left in filtrate then reabsorbed for K, reduced ECF activates RAAS
5
Q
Diuretics causing hyperkalaemia and how
A
K sparing and aldosterone
Decrease in ENaC means filtrate is positive so K reabsorption not favoured
