Diuretics

Question 0

Furosemide

Answer 0

Lasix , Loop diuretic
Widely used during and peri-CPB
2 hour effect
Wide therapeutic window

Question 1

Acetazolamide

Answer 1

Diamox , Carbonic anhydrase inhibitor
Glaucoma
High altitude sickness
Induces metabolic acidosis, not used on CPB

Question 2

Ethacrynic acid

Answer 2

Edecrin , Loop diuretic
Used less commonly than Lasix
Greater potential for ototoxicity

Question 3

Bumetanide

Answer 3

Bumex
Lesser used loop diuretics
Used as second option if not achieving desired result

Question 4

Chlorothiazide

Answer 4

Diuril
Thiazide diuretic
Original diuretic used for edema
Only thiazide for parenteral use

Question 5

Hydrochlorothiazide

Answer 5

HCTZ , Microzide
Thiazide diuretic
Similar to chlorothiazide but can’t give parenterally
Mix with losartan = hyzaar

Question 6

Chlorthalidone

Answer 6

Hygroton
Thiazide-like diuretic
HTN

Question 7

Indapamol

Answer 7

Lozol
Thiazide-like diuretic
Helpful in Renal failure
Excreted via GI tract

Question 8

Spironolactone

Answer 8

Aldactone
Direct aldosterone antagonist
Potassium sparring diuretic
DOC for liver failure w/ edema
Can't be used in Addison's

Question 9

Eplerenone

Answer 9

Inspra
Direct aldosterone antagonist
Potassium sparing diuretic
Can’t be used in Addison’s

Question 10

Triamterene

Answer 10

Dyrenium
Indirect aldosterone antagonist
Potassium sparing diuretic
Can be used in Addison’s

Question 11

Amiloride

Answer 11

Indirect aldosterone inhibitor
Potassium sparing diuretic
Can be used in Addison’s

Question 12

Mannitol

Answer 12

Osmitrol
Osmotic diuretic
MUST be given IV SLOWLY or profound hypotension
Diarrhea if given enterally
Helps cerebral edema
20% solution 
12.5 g with little/no UO = stop

Question 13

Torsemide

Answer 13

Demadex
Lesser used loop diuretics
Used as second option if not achieving desired result

Question 14

Metolazone

Answer 14

Zaroxolyn

Thiazide like diuretic