Anti Arrhythmics Flashcards
Quinidine
Quinidex
Oral
Rarely used because of toxic side effects
Cinchonism and torsades de point
Disopyramide
Norpace
Class Ia Sodium channel blocker
Moderate negative negative inotropic and increase in SVR
May induce HF
Procainamide
Pronestyl, Procan
Most widely used class Ia sodium channel blocker
May cause reversible SLE
Lidocaine
Xylocaine Class Ib sodium channel blocker Only given IV, Wide therapeutic window Effects sick heart tissue more than healthy DOC for ventricular arrhythmias
Mexiletine
Mextil
Tocainide
Tonocard
Last option if not compatible with other Ib
Irreversible pulmonary fibrosis
Flecainide
Tambocor
Given orally
Dramatically slows conduction and automaticity
Used particularly for PVCs
Propafenone
Rhythmol
Given orally
Broad spectrum
SVTs
Propanolol
Class II antiarrhythmic
Beta adrenoceptor blocker
Inderal
Metoprolol
Toprol XL, Lopressor
Most common beta blocker for arrhythmias
Esmolol
Brevibloc
Given IV, short acting
Common for surgery and emergencies
Amiodarone
Cordarone, class III antiarrhythmic, potas channel blocker
Broad spectrum antiarrhythmic
DOC for A fib but causes pulm fibrosis and ARDS
Very long half life, months, requires very high loading dose
800-1600mg/day
Dronedarone
Multaq
Class III antiarrhythmic, potassium channel blocker
Shorter half life, less side effects
Risk of death limits its use
Sotatol
Betapace, Sorine
Class III antiarrhythmic, potassium channel blocker
Nonselective beta blocker
Ideal for post MI b/c it lowers O2 demand
Dofetilide
Tikosyn, Class III antiarrhythmic, potassium channel blocker
Not used a lot
DOC for afib with HF
