Diuretic

Question 1

Diuretic General AEs

Answer 1

• GI effects
  > N/V/D
• Hypotension
• Dehydration
  > fluid volume deficit
• Fluid & electrolyte disturbances
  > Na & K
• Fluid rebound

Question 2

Diuretics General Overview

MOA
indications

Answer 2

• MOA
  > act on kidneys to incr urine output
• Indications
  > HTN (reduce intravascular vol)
  > Fluid overload/edema (HF, pulmonary edema, kidney/liver failure)
  > Glaucoma (dcr IOP)
  > Hyperkalemia (remove excess K)

Question 3

Diuretics General Contraindications

Answer 3

• Pregnancy/lacation
• Severe renal failure
• Hypotension
• Dehydration
• Drug-Drug:
  > Digoxin: incrd K loss may occur
  > Anticoags: reduced effectiveness
  > Antidiabetics: reduced effectiveness
  > Lithium: incrd risk of toxicity

Question 4

Furosemide (Lasix) - Class & MOA

Answer 4

• Class: Loop Diuretic
• MOA: inhibits reabsorp of NaCl in loop of Henle which causes a greater degree of diuresis than other diuretics (water follows Na)

Question 5

Furosemide (Lasix) - Indications & Route/Dose

Answer 5

• Indications
  > Conditions of fluid overload
  > Hyperkalemia
• Route/Dose
  > oral
  > IVP (slow IVP 20mg/min)
  > may be given IM or IV gtt

Question 6

Furosemide - Contraindications

Answer 6

• General slide
• Ototoxic drugs
• Sulfa allergy

Question 7

Furosemide - AEs

Answer 7

• General slide
• Hypokalemia
• CNS effects: paresthesia, ototoxicity
  > IVP slowly to prevent

Question 8

Furosemide - Nursing Considerations

Answer 8

• Potassium supplements
• IV = fall risk
• Take in AM
• Daily weight
• Symps of hypotension & hypokalemia = call PCP
• Maintain fluid intake
• Factors of Fluid Loss: diarrhea, vomiting, excessive heat, sweating