DIT Renal 1. Basics Flashcards
What are the stimulators of renin release?
- low renal BP
- low Na+ delivery to the distal tubule
- High sympathetic tone (beta 1 receptor)
A 40 yo patient of yours weighs 100 kg. What is her estimated plasma volume?
ECF = 20% of weight = 20 L
Plasma volume = 5 L
What artery prevents a horseshoe kidney from ascending in the abdomen?
inferior mesenteric artery
In what manner do the ureters cross the uterine artery which helps you identify these structures during pelvic surgery?
water under the bridge
ureters pass under the uterine artery
What are the side effects of Potter’s Syndrome?
POTTER
Pulmonary hypoplasia Oligohydramnios Twisted skin Twisted face Extreme defects Renal agenesis
constriction of afferent arteriole
RPF: increased
GFR: increased
FF: no change
constriction of efferent arteriole
RPF: decreased
GFR: increased
FF: increased
dilation of afferent arteriole
RPF: increased
GFR: increased
FF: no change
dilation of efferent arteriole
RPF: increased
GFR: decreased
FF: decreased
increase in serum protein
RBF: no change
GFR: decreased
FF: decreased
ureter stone obstruction
RBF: no change
GFR: decreased
FF: decreased
ACEI
RBF: increased
GFR: decreased
FF: decreased
Indomethacin, Naprosyn, Ibuprofen
RBF: decreased
GFR: decreased
FF: no change
What effect will a renal stone that obstructs the ureter have on GFR and FF?
GFR: increased
FF: increased
What fundamental problem creates Potter’s syndrome?
malformation of ureteric bud –> bilateral renal agenesis
