Distribution Flashcards
1
Q
Four compartments of distribution
A
One compartment (intravascular)
Two compartment (intravascular- interstitial)
Multi compartment (extracellular - intracellular)
Tissue reservoir
2
Q
Factors affecting VD
A
Liver failure
Renal failure
Fluid retention
Decreased plasma protein binding
Increase in body fluid
Inversely proportional
Dehydration
3
Q
Volume of distributions
A
Term to qualify the distribution of the drug between the plasma & the body
