Bioavailability& Absorption Flashcards
1
Q
What is bioavailability?
A
Is the amount of administered drug that reached systemic circulation
2
Q
Factors related to drug
A
Formulation, lipid solubility valency, degree of ionization, dosage form.
3
Q
Pharmokinetic?
A
What the body does to the drug.
4
Q
Pharmodynamic
A
What the drug dues to the body
5
Q
Sites of first pass metabolism
A
Liver, lungs, intestinal wall
6
Q
First metabolism?
A
Metabolism of the drug before reaching the systemic circulation
7
Q
Route of administration
A
IV = alveolar = sublingual > im> SC > intestinal> rectal>skin
8
Q
ADME?
A
Absorption, distribution, metabolism, excretion
