DISRUPTIVE, IMPULSE-CONTROL AND CONDUCT DISORDERS; NEURODEVELOPMENTAL DISORDERS Flashcards
1
Q
what is the diagnostic criteria for ADHD
A
- 6+ symptoms of hyperactivity or inattentiveness
- some present prior to age 12
- clear impairement in 2+ settings
2
Q
what is the treatment of ADHD
A
- stimulants (methylphenidate and amphetamines) 1st line for 6+ years.
- 2nd line atomoxetine
- 3rd line clonidine, guafacine.
3
Q
what is the MOA of stimulants
A
- methylphenidate - blocks reuptake of dopamine and NE
- amphetamines - blocks reuptake and stimulates dopamine release
4
Q
what are common SE of stimulants
A
- reduced appetite
- insomnia
- emotional lability
- weight loss
- tics
5
Q
what is the MOA of atomoxetine
A
NE reuptake inhibitor
6
Q
what is the CI for atomoxetine
A
- use within 14 days of an MAOI
- glaucoma
- pheochromocytoma
- arrhythmia or heart disease
7
Q
what is the MOA of clonidine or guafacine
A
stimulate alpha 2 adrenergic receptors in the CNS
8
Q
what is the SE of clonidine
A
- sedation
- bradycardia
9
Q
what are the screening tools fr ASD
A
MCHAT (16-30 mo)
10
Q
what is the mutation that causes Rett disorder
A
MECP2 gene
11
Q
what are signs of rett disorder
A
- deceleration of head growth
- loss of fine motor, intellectual, and communication abilities
12
Q
what is the diagnostic criteria for oppostional defiant disorder
A
spiteful, vindictive, defiant or angry behavior for 6+ months.
13
Q
what is the treatment for oppositional defiant disorder
A
psychotherapy as 1st line
14
Q
what is the diagnostic criteria for conduct disorder
A
- agression and violation of the rights of others
- for at least 12 months
