Disorders of the Nose Flashcards
Definition of allergic rhinitis
- inflammation of the mucous membranes of the nose, eyes, eustachian tubes, middle ear, sinuses and pharynx
- triggered by IgE mediated response
Complications of allergic rhinitis
- Otitis media
- ETD
- Sinusitis (acute and chronic)
- impairment in quality of life
What is early response
With allergen re-exposure, the specific protein binds to the IgE on the mast cells resulting in an immediate and delayed release of inflammatory mediators (histamines) which lead to symptoms of AR
What is late response
4-10 hours after allergen exposure, you have a second release of inflammatory mediators (eosinophils), continued inflammation with persistent symptoms
Symptoms of allergic rhinitis
- rhinorrhea
- sneezing
- itching
- post nasal drip/sore throat
- nasal congestion/obstruction
- increased lacrimation/red eyes
- eye swelling
- fatigue/drowsiness
What is allergic salute?
transverse crease across the nasal bridge d/t upward rubbing of the nose
PE of nose in AR
Allergic salute
Nasal mucosa is pale and boggy
thin, watery nasal secretions
What are allergic shiners
dark, swollen, infraorbital tissue secondary to vasodilation and/pr congestion
PE of eyes in AR
conjunctiva injected and edematous with clear drainage
allergic shiners
PE of ears in AR
TM retraction, air fluid levels or bubbles
PE of throat in AR
Pharynx is generally unremarkable
DDX of allergic rhinitis
Nonallergic rhinitis syndromes
What are some diagnostic tests for allergic rhinitis
- Blood (supportive but not sensitive or specific)
i. e. Eosinophils in CBC, IgE elevation - Nasal smears (eosinophils)
- Skin testing (immediate hypersensitivity)
- RAST (radioallergosorbent test)
Allergic rhinitis treatment
- Avoidance of allergens/prevention
- pharmacologic treatment
- immunotherapy
Examples of pharmacotherapy treatment for AR
- Intranasal steroids
- antihistamines
- leukotriene antagonist
- mast cell stabilizer- Cromolyn