Disorders of the Musculoskeletal System (Bone & Joints) Flashcards
Osteitis Deformans (PAGETS)
Older males, bone deformities, mosaic layers, osteoporosis circumscipta (skull) bowing tibia, pseudofractures, cortical thickening, osteoblastic - osteoclastic activity, saber skin, deafness, coarsened trabeculae, IVORY WHITE VERTEBRA (leads to osteosarcoma,
Osteitis Deformans (PAGETS)
Increased alkaline phosphatase (40xs)
Neurofibromatosis (VON RECKLINGHAUSENS)
Genetically inherited, autosomal dominant, chromosome 17
Neurofibromas
Can compress nerves, cafe-au-lait spots (neurofibromatosis)
Fibrous Dysplasia
Bone thinning, lesions/growths in bones
Monostotic
One bone
Polyostotic
Many bones
McCune (ALBRIGHT’S SYNDROME)
Yound girls, several bones involved, endocrine related, precocious (early puberty) (fibrous Dysplasia)
Hemangioma
MC benign bone tumor of the vertebra
Osteochondroma
MC benign bone tumor of the body (sessile[no stalk] & pedunculated)
Osteogenesis Imperfecta (BRITTLE BONE)
Genetic, abnormal collagen, fractures, blue sclera
Osteopetrosis
Overgrowth & sclerosis bone, however, weak & fractures
Osteoporosis
Post menopausal, increased fractures
Osteomyelitis
Staph infection in bone
Pott’s Disease
TB of spine, spreads lungs –> thoracics –> eats joint –> vertebra collapses –> increase kyphosis = Gibbus deformity (sharp angle)