Disorders Of The Endocrine Stystem And Hormones Flashcards
An under secretion of a hormone within the body.
Hyposecretion
An over secretion of a hormone within the body.
Hypersecretion
A mechanism that works to “reverse” or “decrease” changes in the body.
Ex: Hypothalamus- pituitary feedback mechanism.
Negative feedback mechanism/loop
A mechanism that serves to “increase” the effect of an action.
Ex: oxytocin feedback loop
Positive feedback mechanism
Cause: Insufficient production of HGH during Hollywood.
Effect: Causes an abnormally short stature.
Treatment: Injections of HGH.
Dwarfism
Pituitary Gland
Cause: Excess production of HGH prior to puberty.
Effect: Abnormal growth of long bones in the skeleton.
Treatment: microsurgery of pituitary, radiation treatment of gland tissue.
Gigantism
Pituitary Gland
Cause: Excess HGH production during adult years.
Effect: causes thickening of bone tissue. Causes abnormal growth of head, hands and feet. Also causes spinal deformities.
Treatment: Surgical removal of tumour causing too much HGH to be released. Radiation of tumour. Injection of HGH blocking drug.
Acromegaly
Pituitary Gland
Cause: insufficient production of ADH.
Effect: Increased thirst and dehydration, production of high amounts of dilute urine, Enlarged urinary bladder.
Treatment: Injections of ADH to reverse effects.
Diabetes insipidus
Pituitary Gland
~Condition where adults become obese, lose appetite and are often tired because of under production of Thyroxin.
Treatment: drugs that have Thyroxin in them.
Myxedema
(Thyroid Gland)
Hypo Secretion of Thyroxin
~Condition in children where they are often short/ stalky and often cognitively delayed.
Treatment: drugs having Thyroxin
Congenital Hypothyroidism or cretinism
(Thyroid Gland)
Hypo Secretion of Thyroxin
~a condition caused by a lack of iodine in the diet. This causes a decreased production of Thyroxin.
~Patients end up with a swollen thyroid gland. Looks like a large growth on the neck.
Treatment: increase Iodine intake
Goiter
(Thyroid Gland)
Hypo secretion of thyroxin
~ Condition where there is an increased metabolism (“hyperness”) in a person.
~ increased sweating
~muscle weakness
~ protruding eyes
Treatment: Surgical removal of thyroid gland, thyroid blocking drugs.
Graves’ disease
(Thyroid Gland)
Hyper secretion of Thyroxine
~known as Juvenile or insulin dependent diabetes. Occurs in individuals under twenty years old.
Cause: Beta cells of Islets of Langerhans do not produce enough insulin.
Result: abnormally high levels of sugar (glucose) in the blood.
Symptoms: Fatigue, thirst, weightloss, frequent urination, blindness.
Treatment: Insulin injections(usually for rest of life)
Diabetes Mellitus
Type 1 Diabetes
Disorders of the Pancreas
~ known as “adult onset diabetes”. Usually occurs in individuals over 40 years old.
~insulin is produced by pancreas but cells “do not recognize” it. Cells Do use the sugar found in the blood.
Treatment: Strict control of carbohydrate intake to reduce amount of sugar in the blood.
Type 2 diabetes
Disorders of the pancreas
- caused by excessive ACTH which raises the level of cortisol/aldosterone
- symptoms include high bp, high blood sugar, muscle weakness and edema( fluid accumulation)
- can be treated by drugs to block the production of the hormones causing problems
- the cause may also be a tumour requiring surgery
Cushings syndrome
Disorders related to the Adrenal glands