Disorders of Development Flashcards
1
Q
What is precocious puberty?
A
When secondary sexual characteristics appear before 8 years of age in girls and 9 years in boys
2
Q
What are the two types of precocious puberty?
A
1) Gonadotrophin-dependent precocious puberty (GDPP/central) = due to premature activation of the hypothalamo-pituitary-gonadal axis
2) Gonadotrophin-independent precocious puberty (GIPP/peripheral) = due to autonomous secretion of sex steroids
3
Q
In which condition do you use a gonadotropin releasing hormone stimulation test to confirm diagnosis?
A
Precocious puberty
4
Q
In ____/_______ GRH is high and in ____/_________ GRH is low.
A
GDPP/central
GIPP/peripheral
