Disorders of Cranial Nerves Flashcards

1
Q

The cranial nerve signs from bilateral CN II indicate the lesson is located where

A

Midbrain

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2
Q

A combination of cranial nerve signs from CN III, IV, VI indicate the lesion is where

A

Superior orbital fissure

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3
Q

A combination of cranial nerve signs from CN VI + VII indicate the lesion is where

A

Pons

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4
Q

A combination of cranial nerve signs from CN VI + VIII indicate the lesion is where

A

Cerebellopontine angle

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5
Q

What does an unusual combination go cranial nerves potentially suggest

A

Chronic or malignant meningitis

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6
Q

What does pure motor cranial nerve signs potentially suggest

A

Myasthenia gravis

- chronic autoimmune neuromuscular disease

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7
Q

What is the symptomss of myasthenia gravis

A

droopy eyelids

double vision

difficulty making facial expressions

problems with chewing anddifficulty swallowing

slurred speech

weak arms, legs or neck

shortness of breathand occasionally serious breathing difficulties

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8
Q

Wha are cranial nerve signs that don’t necessarily imply a cranial nerve lesion

A

eye movement disorders

facial weakness,

difficulty swallowing after a stroke

double vision in myasthenia

thyroid eye disease

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9
Q

What are the potentially sites where cranial nerves can be damaged

A

Within the brain
Crossing subarachnoid space
Outside the skull

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10
Q

How can cranial nerves be damaged within the brain

A

Ischaemia

Tumour

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11
Q

How can cranial nerves be damaged crossing sub arachnoid space

A

Meningits

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12
Q

What is an example of how cranial never can be damaged outside the skull

A

base of skull tumours arising in nasopharynx

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13
Q

What is optic neurtis

A

Demyelination within the optic nerve (CN II)

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14
Q

What is optic neuritis associated with

A

Multiple sclerosis

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15
Q

What is the signs and symptoms of optic neuritis

A

monocular visual loss

pain on eye movement

reduced visual acuity

reduced colour vision

optic disc may be swollen

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16
Q

What has control over pupil constriction

A

Parasympathetic system

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17
Q

What has control over pupil dilation

A

Sympathetic system

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18
Q

What is the potential causes of small pupils,

A
Old age
Bright light
“Miotic” eye drops 
Opiate overdose
Horner’s Syndrome
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19
Q

What is the potential causes of dilated pupils

A
Youth
Dim lighting
Anxiety, excitement
“Mydriatic” eye drops
Amphetamine, cocaine overdose
Third nerve palsy
Brain death
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20
Q

Loss of parasympathetic and sympathetic input has what affect on the pupil

A

Parasympathetic - Fixed dilated pupil

Sympathetic - constricted pupil

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21
Q

What is a common cause of parasympathetic input loss to the pupil

A

Complete third nerve palsy (CN III, oculomotor)

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22
Q

What is the two causes of third nerve palsy

A

Microvascular - never cant function due to lack of blood supply

Compressive

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23
Q

What are two examples of microvascular third nerve palsy

A

Hypertension

Diabetes

24
Q

What are two examples of compressive third nerve palsy

A

Posterior communicating artery aneurysm

Raised ICP

25
Q

What is the symptoms of third nerve palsy

A

Ptosis - closed eye lid
Eye deviated outward and downwards

Diplopia - double vision

Enlarged pupi

Failure of abduction

26
Q

What is the difference between microvascular third nerve palsy and compressive third nerve palsy

A

Microvascular is painless and the pupil is spared compared to compressive which is painful and the pupil is affected

27
Q

What is 5 different eye movement disorders

A

Isolated third nerve palsy

Isolated fourth nerve palsy

Isolated sixth nerve palsy

(Combination of the above)

Supranuclear gaze palsy

Nystagmus

28
Q

What is the symptoms of fourth nerve palsy

A

Vertical double vision

Affects outward rotation (extortion)

29
Q

What is the symptoms of sixth nerve palsy

A

Cannot move eye to the outside
side by side double vision
eye debated to the middle of your nose

30
Q

What is the potential causes of sixth nerve palsy

A

Idiopathic

diabetes

meningitis

raised intracranial pressure

31
Q

What is supra nuclear gaze

A

Inability to look in a particular direction (due to loss of voluntary eye movements) as a result of cerebral impairment

32
Q

What is the causes of nystagmus (rapid eye movements)

A

Congenital
Central vestibular / brainstem disease
Cerebellar disease
Toxins (medication and alcohol)

33
Q

What is the symptoms of nystagmus

A

Serious visual impairments

Peripheral vestibular problems - vertigo

34
Q

What is examples of lower motor neurone facial paralsysis (CN VII)

A

Bells palsy
Lyme
Sarcoid

35
Q

What occurs in bells palsy

A

Idiopathic facial nerve palsy due to lower motor neurone lesion

36
Q

What is the symptoms of bells palsy

A

Unilateral Facial weakness
drooping mouth and eyes
Cant raise eye brows

often proceeded by pain behind the ear

risk of corneal damage

37
Q

What is the treatment of bells palsy

A

Steroids - usual good recovery

38
Q

what is causes of upper motor neurone facial paralysis

A

stroke

tumour

39
Q

What is trigeminal neuralgia (CN V)

A

Paroxysmal attacks of lacinanting due to triggers

40
Q

What is the causes of trigeminal neuralgia

A

Happens middle and old age

caused by vascular loop leading to compression of fifth cranial nerve in posterior fossa

41
Q

What is treatment of trigeminal neuralgia

A
Carabamezepine 
Surgical option (if medication resistance)
42
Q

What is vestibular neuritis (CNVIII)

A

Labyrinthitis - is inflammation of the inner ear

43
Q

What is the symptoms of vestibular neuritis

A

Disabling vertigo
Vomiting
hearing loss
ringing in the ears

44
Q

What is bulbar palsy

A

Bilateral lower motor lesion affecting CN IX- XII

45
Q

What is the potentially causes of bulbar palsy

A

Motor neurone disease polio,
tumours,
vascular lesions of the medulla
syphilis

46
Q

What is the symptoms of bulbar palsy

A
  • wasted, fasciculating tongue
  • dysarthria
  • dysphonia
  • dysphagia

(beware of feeding these patients)

47
Q

What is pseudo bulbar palsy

A

Bilateral upper motor lesion

48
Q

What is the potential causes pseudo bulbar palsy

A

vascular lesions of both internal capsules

Motor neurone disease

49
Q

What is the symptoms of pseudobulbar palsy

A
  • dysarthria
  • dysphonia
  • dysphagia
  • spastic, immobile tongue
  • brisk jaw jerk
  • brisk gag reflex
50
Q

What is the facial motor nucleus divided into and supply

A

Upper - supplies facial musculature above zygomatic arch

Lower - supplies facial musculature below zygomatic arch

51
Q

What is the innervation of the upper part of the facial nucleus

A

Innervation from contralateral and ipsilateral side of the brain

52
Q

What is the innervation of the lower part of the facial nucleus

A

Innervation only from contralateral side

53
Q

If lesion occurs in lower motor neurones what is the pathology

A

Ipsilateral paralysis of upper and lower facial musculature

54
Q

If lesion occurs in the upper motor neurones what is the pathology

A

Paralysis of contralateral facial musculature

55
Q

What is symptoms of an upper motor lesion facial paralysis

A

Drooping of face
Cant smile on affected side
can raise eyebrow

56
Q

How do you still have control over upper musculature of the face in upper motor lesion facial paralysis

A

as upper musculatral as bilateral innervation from ipsilateral side as well

57
Q

What is the symptoms of lower motor lesions facial paralysis

A

Drooping on affected side of the face
cant raise eye brow on affected side of the face
cant smile on affected side of the face