Disorders of Cranial Nerves Flashcards

1
Q

The cranial nerve signs from bilateral CN II indicate the lesson is located where

A

Midbrain

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2
Q

A combination of cranial nerve signs from CN III, IV, VI indicate the lesion is where

A

Superior orbital fissure

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3
Q

A combination of cranial nerve signs from CN VI + VII indicate the lesion is where

A

Pons

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4
Q

A combination of cranial nerve signs from CN VI + VIII indicate the lesion is where

A

Cerebellopontine angle

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5
Q

What does an unusual combination go cranial nerves potentially suggest

A

Chronic or malignant meningitis

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6
Q

What does pure motor cranial nerve signs potentially suggest

A

Myasthenia gravis

- chronic autoimmune neuromuscular disease

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7
Q

What is the symptomss of myasthenia gravis

A

droopy eyelids

double vision

difficulty making facial expressions

problems with chewing anddifficulty swallowing

slurred speech

weak arms, legs or neck

shortness of breathand occasionally serious breathing difficulties

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8
Q

Wha are cranial nerve signs that don’t necessarily imply a cranial nerve lesion

A

eye movement disorders

facial weakness,

difficulty swallowing after a stroke

double vision in myasthenia

thyroid eye disease

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9
Q

What are the potentially sites where cranial nerves can be damaged

A

Within the brain
Crossing subarachnoid space
Outside the skull

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10
Q

How can cranial nerves be damaged within the brain

A

Ischaemia

Tumour

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11
Q

How can cranial nerves be damaged crossing sub arachnoid space

A

Meningits

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12
Q

What is an example of how cranial never can be damaged outside the skull

A

base of skull tumours arising in nasopharynx

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13
Q

What is optic neurtis

A

Demyelination within the optic nerve (CN II)

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14
Q

What is optic neuritis associated with

A

Multiple sclerosis

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15
Q

What is the signs and symptoms of optic neuritis

A

monocular visual loss

pain on eye movement

reduced visual acuity

reduced colour vision

optic disc may be swollen

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16
Q

What has control over pupil constriction

A

Parasympathetic system

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17
Q

What has control over pupil dilation

A

Sympathetic system

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18
Q

What is the potential causes of small pupils,

A
Old age
Bright light
“Miotic” eye drops 
Opiate overdose
Horner’s Syndrome
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19
Q

What is the potential causes of dilated pupils

A
Youth
Dim lighting
Anxiety, excitement
“Mydriatic” eye drops
Amphetamine, cocaine overdose
Third nerve palsy
Brain death
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20
Q

Loss of parasympathetic and sympathetic input has what affect on the pupil

A

Parasympathetic - Fixed dilated pupil

Sympathetic - constricted pupil

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21
Q

What is a common cause of parasympathetic input loss to the pupil

A

Complete third nerve palsy (CN III, oculomotor)

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22
Q

What is the two causes of third nerve palsy

A

Microvascular - never cant function due to lack of blood supply

Compressive

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23
Q

What are two examples of microvascular third nerve palsy

A

Hypertension

Diabetes

24
Q

What are two examples of compressive third nerve palsy

A

Posterior communicating artery aneurysm

Raised ICP

25
What is the symptoms of third nerve palsy
Ptosis - closed eye lid Eye deviated outward and downwards Diplopia - double vision Enlarged pupi Failure of abduction
26
What is the difference between microvascular third nerve palsy and compressive third nerve palsy
Microvascular is painless and the pupil is spared compared to compressive which is painful and the pupil is affected
27
What is 5 different eye movement disorders
Isolated third nerve palsy Isolated fourth nerve palsy Isolated sixth nerve palsy (Combination of the above) Supranuclear gaze palsy Nystagmus
28
What is the symptoms of fourth nerve palsy
Vertical double vision | Affects outward rotation (extortion)
29
What is the symptoms of sixth nerve palsy
Cannot move eye to the outside side by side double vision eye debated to the middle of your nose
30
What is the potential causes of sixth nerve palsy
Idiopathic diabetes meningitis raised intracranial pressure
31
What is supra nuclear gaze
Inability to look in a particular direction (due to loss of voluntary eye movements) as a result of cerebral impairment
32
What is the causes of nystagmus (rapid eye movements)
Congenital Central vestibular / brainstem disease Cerebellar disease Toxins (medication and alcohol)
33
What is the symptoms of nystagmus
Serious visual impairments Peripheral vestibular problems - vertigo
34
What is examples of lower motor neurone facial paralsysis (CN VII)
Bells palsy Lyme Sarcoid
35
What occurs in bells palsy
Idiopathic facial nerve palsy due to lower motor neurone lesion
36
What is the symptoms of bells palsy
Unilateral Facial weakness drooping mouth and eyes Cant raise eye brows often proceeded by pain behind the ear risk of corneal damage
37
What is the treatment of bells palsy
Steroids - usual good recovery
38
what is causes of upper motor neurone facial paralysis
stroke | tumour
39
What is trigeminal neuralgia (CN V)
Paroxysmal attacks of lacinanting due to triggers
40
What is the causes of trigeminal neuralgia
Happens middle and old age | caused by vascular loop leading to compression of fifth cranial nerve in posterior fossa
41
What is treatment of trigeminal neuralgia
``` Carabamezepine Surgical option (if medication resistance) ```
42
What is vestibular neuritis (CNVIII)
Labyrinthitis - is inflammation of the inner ear
43
What is the symptoms of vestibular neuritis
Disabling vertigo Vomiting hearing loss ringing in the ears
44
What is bulbar palsy
Bilateral lower motor lesion affecting CN IX- XII
45
What is the potentially causes of bulbar palsy
Motor neurone disease polio, tumours, vascular lesions of the medulla syphilis
46
What is the symptoms of bulbar palsy
- wasted, fasciculating tongue - dysarthria - dysphonia - dysphagia (beware of feeding these patients)
47
What is pseudo bulbar palsy
Bilateral upper motor lesion
48
What is the potential causes pseudo bulbar palsy
vascular lesions of both internal capsules | Motor neurone disease
49
What is the symptoms of pseudobulbar palsy
- dysarthria - dysphonia - dysphagia - spastic, immobile tongue - brisk jaw jerk - brisk gag reflex
50
What is the facial motor nucleus divided into and supply
Upper - supplies facial musculature above zygomatic arch Lower - supplies facial musculature below zygomatic arch
51
What is the innervation of the upper part of the facial nucleus
Innervation from contralateral and ipsilateral side of the brain
52
What is the innervation of the lower part of the facial nucleus
Innervation only from contralateral side
53
If lesion occurs in lower motor neurones what is the pathology
Ipsilateral paralysis of upper and lower facial musculature
54
If lesion occurs in the upper motor neurones what is the pathology
Paralysis of contralateral facial musculature
55
What is symptoms of an upper motor lesion facial paralysis
Drooping of face Cant smile on affected side can raise eyebrow
56
How do you still have control over upper musculature of the face in upper motor lesion facial paralysis
as upper musculatral as bilateral innervation from ipsilateral side as well
57
What is the symptoms of lower motor lesions facial paralysis
Drooping on affected side of the face cant raise eye brow on affected side of the face cant smile on affected side of the face