Disorders

Question 1

Lebers idiopathic stellate neuroretinitis (LISN)

Answer 1

3rd decade
Unilateral 70%
RAPD (75%) with central or cecocentral central APD
+ vitreous cell, papilledema

Question 2

Infectious causes of neuroretinitis

Answer 2

Syphilis
Lyme 
Viral (influenza, mumps coxsackies)
Bartonella 
TB
Toxocara, toxoplasma, DUSN

Question 3

DUSN

Diffuse unilateral subacute neuroretinitis

Answer 3

Ancylostoma caninum or baylisascaris procyonis
Multifocal pigment changes from moving worm.
RADP
decr va

Question 4

Ddx for papillitis with macular star

Answer 4

Levers idiopathic stellate neuroretinitis 
Syphilis, TB
HTN
Coccidiomycosis
Cat scratch 
AION and DUSN (Mac star rare)

Question 5

HIV retinopathy

Answer 5

Occurs In 50% of HIV pts
Due to complement deposition
Can see CWS, Roth spots, heme

Question 6

Toxic retinopathy dosages

Answer 6

Gentamicin (more than 0.1 mg)
Chloroquine (>3 mg/kg/d 300 g total)
Hydroxychlorouine (>6.5 mg/kg/d or 700 g total)
Thioridazine (>1200 mg/d)
Chlorpromazine (1200-2400 mg/d for 12 months)
Tamoxifen (>30 mg/d)

Question 7

Aminoglycosides toxicity

Answer 7

Severe permanent vision loss after injection with macular whitening, hemorrhages, optic atrophy and pigment art changes
Dose of 0.1 mg gentamicin

Question 8

Plaquanil toxicity

Answer 8

Binds to melanin in RPE
Perifoveal mottling the bulls eye maculopathy
Para central scotoma
ERG - enlarged a wave and decreased b wave
>6.5 mg/kg/d or total 700 g

Question 9

Benign retinal degenerations

Answer 9

White without pressure
Pigment clumping
Paving stone degeneration 
Senile retinoschesis
Peripheral micro cystic changes

Question 10

Retinal degenerations that predispose to RD

Answer 10

Lattice degeneration
Snail track degeneration
Zonuloretinal traction tufts
Snowflake degeneration