Disorders

Question 1

Stroke prevalence =
Stroke incidence =
… In …. Die within a year

Answer 1

Prevalence. 5 / 1000
Incidence = 2 / 1000
1 in 3 die within a year

Question 2

Intracerebral haemorrhage mechanisms (4)

Answer 2

Charcot-Bouchard micro aneurysm
Micro bleeds
Haemorrhaging transformation of infarcts
Vasculitis

Question 3

Primary cause of haemorrhaging stroke =

Answer 3

Hypertension

Question 4

Ischaemic stroke:
Failure of …/.. Pumps
Depolarisation and risk in intracellular … Due to:
- … Channel opening
- … Release (…. Receptors, …. Receptors, …. Receptors)

Answer 4

Ischaemic stroke:
Failure of NA/K Pumps
Depolarisation and risk in intracellular CALCIUM Due to:
- CA Channel opening
- GLUTAMATE Release (NMDA Receptors, AMPA Receptors, METABOTROPHIC Receptors)

Question 5

Area around an infarct (stroke) which is possible to save …

Answer 5

Penumbra

Question 6

Stroke R.F:
Smoking X
Alcohol X

Answer 6

Smoking x2

Alcohol x3

Question 7

Pyramidal system (5)

Answer 7

Primary motor cortex, cerebral peduncle a, decussation of the pyramids, descending corticospinal tracts

Question 8

Stroke anterior circulation = …. / …..
Large/small Vessel?
Uni/bi lateral motor deficient?
……. Hemianopia

Answer 8

Stroke anterior circulation = TACI / PACI
LARGE Vessel
UNIlateral motor deficient?
HOMONYMOUS Hemianopia

Question 9

Posterior circulation - …..
Large/small vessel
…… Hemianopia
Uni/bilateral motor signs?

Answer 9

Posterior circulation - POCI
LARGE vessel
PURE Hemianopia
BIlateral motor signs

Question 10

Lacunar - …..
large/small vessel?
… stroke

Answer 10

Lacunae - LACI
SMALL vessel
Sensorimotor stroke

Question 11

Stroke antiplatelet therapy:
.... 300mg, 
..... 75mg
OR
.... 75mg,
..... 200mg

Answer 11

Aspiring 300mg, clopidogrel 75mg
OR
Aspiring 75mg, dipyridamole 200mg

Question 12

TIA - an …. Loss of ….. Cerebral or … function with symptoms lasting less than …. Hours.
Is presumed to be due to …. Or …. Vascular disease

Answer 12

TIA - an ACUTE loss of FOCAL cerebral or MONOCULAR function with symptoms lasting less than 24 hours
Is presumed to be due to EMBOLIC or THROMBOTIC vascular disease

Question 13

Admit patient with TIA if have … (2)

Answer 13

Atrial fibrillation

Carotid stenosis

Question 14

Ischaemic strokes = …%

Haemorrhaging strokes = ….%

Answer 14

70-80%

20-30%