Disorder and Diseases

Question 1

mutations in oncogenes and tumor supressor genes

Answer 1

Cancer

Question 2

mutation linked in breast(cancer)

Answer 2

BRCA1/2 genes

Question 3

mutations in lung(cancer)

Answer 3

EGFR and KRAS Genes

Question 4

mutation that involves translocation affecting genes

Answer 4

Leukemia

Question 5

Treatment that targets rapid dividing cells(cancer cells)

Answer 5

Chemotherapy

Question 6

Inherited mutations in the TP53 gene, leading to a high risk of cancer at an early age

Answer 6

Li-Fraumeni Syndrome

Question 7

Mutation in RB1 gene, white reflection in the pupil(leukocoria), vision loss, eye redness. Can be treated with chemo, radiation, and enucleation

Answer 7

Retinoblastoma

Question 8

caused by defect in nucleotide excision repair(NER), leading to inability to repair UV-induced DNA damage. Extreme sensitivity to UV light, high risk of skin cancer. Preventions: avoid sunlight, sunscreen, regular dermatology.

Answer 8

Xeroderma Pigmentosum(XP)

Question 9

Mutation in ATM gene, results in lack of muscle coordination, small; dilated blood vessels), increased risk of leukemia and lyphoma. Treatments are physical therapy, immune system support, screening for early cancer detection

Answer 9

Ataxia-Telangiectasia(A-T)

Question 10

Refers to any irregularity or dysfunction in the cell cycle

Answer 10

Disorder

Question 11

Cell cycle malfunction (specific condition caused by dysfunction)

Answer 11

Disease