Diseases and their Antibiotics

Question 1

Strep throat

Answer 1

1. Penicillin V
2. Cephalexin
3. Erythromycin (or one of the other macrolides) if penicillin allergy.

Question 2

Staph (MSSA)

Answer 2

1. Oxacillin
2. Amoxicillin + clavulanic acid
3. Vancomycin

Question 3

Staph (MRSA)

Answer 3

1. Vancomycin
2. Linezolid
3. Daptomycin

Question 4

Strep pneumo

Answer 4

1. Penicillin G
2. Cefazolin
3. Ceftriaxone (if meningitis)
4. Vancomycin (if ceftriaxone-resistant meningitis)

Question 5

Gonorrhea

Answer 5

Ceftriaxone + doxycycline/azithromycin

Question 6

Chlamydia

Answer 6

Doxycycline/azithromycin

Question 7

Syphilis

Answer 7

1. Penicillin G benzathine

2. Doxycycline or minocycline if allergic to penicillins.

Question 8

C diff

Answer 8

1. Metronidazole
2. Vancomycin
3. Fidaxomicin (works well against recurrent strains)

Question 9

H. pylori

Answer 9

Metronidazole + clarithromycin + omeprazole

Question 10

Lyme disease

Answer 10

1. Doxycycline (but not to children or pregnant women)
2. Ceftriaxone
3. Amoxicillin

Question 11

Rickettsia

Answer 11

1. Doxycycline (even to kids)

2. Chloramphenicol

Question 12

UTI

Answer 12

1. TMP/SMX
2. Nitrofurantoin
3. Fosfomycin

Question 13

Bacterial meningitis (empirical treatment)

Answer 13

1. Ceftriaxone + vancomycin
2. If caused by listeria - ampicillin.
   Rifampin for prophylaxis.

Question 14

Strict anaerobes (Gm + or -)

Answer 14

1. Metronidazole
2. Clindamycin
3. Piperacillin + tazobactam

Question 15

Strict anaerobes (Gm +)

Answer 15

1. Penicillin G
2. Vancomycin
3. Daptomycin

Question 16

Gm -

Answer 16

1. Amoxicillin + clavulanic acid
2. Piperacillin + tazobactam
3. Ceftriaxone
4. Imipenem with cilastatin

Question 17

Pseudomonas

Answer 17

1. Piperacillin + tazobactam
2. Ciprofloxacin/moxifloxacin
3. Ceftazidime

Question 18

ESBL positive Gm -

Answer 18

Imipenem with cilastatin

Question 19

Surgical prophylaxis of skin flora

Answer 19

Cefazolin (IV)