Disease of the heart muscle, pericardium and endocarditis Flashcards
Define acute myocarditis
acute inflammation of the myocardium. The heart becomes flabby with focal haemorrhages and inflammatory infiltrate
What are the symptoms of acute myocarditis
fever
chest pain
SOB
palpations
What are the sign of acute myocarditis
Arrhythmia
Cardiac failure
Acute myocarditis aetiology
mainly caused by enteroviruses - Coxseickie A +B, Echovirus
How do you diagnose acute myocarditis
viral PCR
Throat and stool swap for enterovirus
Throat swab for echovirus
What investigation finding would you discover in acute myocarditis
CXR: cardiac enlargement
ECG: ST elevation or deprivation, T wave inversion, arrhythmia, heart block
Elevated CK / Troponium
How would you treat Acute Myocarditis
Treat underlying cause of infection
Antibiotics if necessary
Bed rest
ACEI, B-blockers, Spironolactone, Digoxin
Define hypertrophic cardiomyopathy
Hypertrophy in the absence of other disease
What is the most common cause of sudden cardiac death in children / young people
Hypertrophic (OBSTRUCTIVE) cardiomyopathy
Which disease is autosomal dominant, which many of the mutations in genes encoding for sacromeric proteins
HOCM
What are the signs and symptoms of HOCM
Asymptomatic Chest pain, dyspnoea, syncope LVOT obstruction Double apex pulsation S4 Jerky carotid pulse Systolic murmur Hypertrophy affecting IV septum
ECG: LV hypertrophy, Q waves inferolaterally
ECHO: diagnostic ASYMMETRY
HOCM
Treatment of HOCM
treat symptoms
mild - amiodarone
b-blockers +/- verapamil
‘banana shaped LV cavity’
HOCM
which kind of murmur is HOCM quite often associated with
mitral regurgitation
A dilated flappy heart of unknown cause that is congenitally X-linked
Dilated cardiomyopathy
Symptoms and signs of dilated cardiomyopathy
arrhythmias, HF, thrombembolism