Disease conditions associated with neoplasms

Question 1

Down syndrome

Answer 1

ALL, AML

Question 2

Xeroderma pigmentosum, albinism

Answer 2

Melanoma
Basal cell carcinoma
Squamous cell carcinomas of the skin (most common)

Question 3

Chronic atrophic gastritis, pernicious anemia, postsurgical gastric remnants

Answer 3

Gastric adenocarcinoma

Question 4

Tuberous sclerosis (facial angiofibroma, seizures, mental retardation)

Answer 4

Giant cell astrocytoma
Renal angiomyolipoma
Cardiac rhabdomyoma

Question 5

Actinic keratosis

Answer 5

Squamous cell carcinoma of the skin

Question 6

Barrett’s esophagus (chronic GI reflux)

Answer 6

Esophageal adenocarcinoma

Question 7

Plummer-Vinson syndrome (decr iron)

Answer 7

Squamous cell carcinoma of the esophagus

Question 8

Cirrhosis (alcoholic, hep B or C)

Answer 8

Hepatocellular carcinoma

Question 9

Ulcerative colitis

Answer 9

Colonic adenocarcinoma

Question 10

Paget’s disease of bone

Answer 10

Secondary osteosarcoma

Fibrosarcoma

Question 11

Immunodeficiency states

Answer 11

Malignant lymphomas

Question 12

AIDS

Answer 12

Aggressive malignant lymphomas (non-Hodgkins)

Kaposi’s sarcoma

Question 13

AI diseases

Answer 13

Lymphoma

Question 14

Acanthosis nigricans (hyperpigmentation and epidermal thickening)

Answer 14

Visceral malignancy (stomach, lung, uterus)

Question 15

Dysplastic nevus

Answer 15

Malignant melanoma

Question 16

Radiation exposure

Answer 16

Leukemia
Sarcoma
Papillary thyroid cancer
Breast cancer